Angina:
Indications for: NITROMIST
Acute attacks and prophylaxis of angina.
Adult Dosage:
1–2 sprays at onset of attack, on or under tongue while sitting; may repeat every 5 minutes as needed; max 3 sprays/15 minutes. May use prophylactically 5–10 minutes before exertion. Do not inhale spray. Do not rinse mouth for 5–10 minutes after use.
Children Dosage:
Not established.
NITROMIST Contraindications:
Concomitant PDE5 inhibitors (eg, sildenafil, vardenafil, tadalafil), riociguat. Severe anemia. Increased intracranial pressure. Acute circulatory failure. Shock.
NITROMIST Warnings/Precautions:
Volume depletion. Hypotension. Acute MI. CHF. Hypertrophic cardiomyopathy. Monitor for tolerance. Product is flammable. Elderly. Pregnancy. Nursing mothers.
NITROMIST Classification:
Nitrate.
NITROMIST Interactions:
See Contraindications. Hypotension potentiated with PDE5 inhibitors, riociguat, antihypertensives, β-blockers, calcium channel blockers, alcohol. May be potentiated by aspirin. Nitroglycerin (IV) may antagonize t-PA, heparin (monitor APTT). Avoid concomitant ergotamine and related drugs. Do not use epinephrine to treat hypotension from nitrate overdose.
Adverse Reactions:
Headache (may be severe), flushing, rash, hypotension.
How Supplied:
Bottles—4.1g (90 metered sprays), 8.5g (230 metered sprays)
