Indications for: SOLODYN

Inflammatory lesions of non-nodular moderate to severe acne.

Adult Dosage:

Swallow whole. Give approximately 1mg/kg once daily for 12wks. Weight-based dosing (45–49kg): 45mg; (50–59kg): 55mg; (60–71kg): 65mg; (72–84kg): 80mg; (85–96kg): 90mg; (97–110kg): 105mg; (111–125kg): 115mg; (126–136kg): 135mg. Renal impairment: reduce dose or extend dosing intervals.

Children Dosage:

<12yrs: not established.

SOLODYN Warnings/Precautions:

Not bioequivalent with other minocycline products. Monitor blood, renal, and hepatic function. Discontinue if superinfection, DRESS syndrome, or autoimmune syndromes develop. Monitor for visual disturbances. Renal or hepatic impairment. Avoid sun or UV light. Pregnancy (Cat.D), nursing mothers: not recommended.

SOLODYN Classification:

Tetracycline antibiotic.

SOLODYN Interactions:

Avoid concomitant penicillins, isotretinoin. Fatal renal toxicity with concomitant methoxyflurane. May need to reduce concomitant anticoagulant dose. Absorption reduced by antacids containing aluminum, calcium, magnesium and iron. May antagonize oral contraceptives. May interfere with fluorescence test.

Adverse Reactions:

Headache, fatigue, dizziness, pruritus; teeth discoloration, delayed skeletal development, intracranial hypertension, C.difficile-associated diarrhea, photosensitivity, hyperpigmentation, hepatotoxicity, skin/hypersensitivity reactions (may be severe).

How Supplied:

Ext-rel tabs—30