Hypertension:
Indications for: TRANDATE
Hypertension.
Adult Dosage:
Initially 100mg twice a day. Titrate at 2–3 day intervals in increments of 100mg twice daily. Usual maintenance: 200–400mg twice daily; max 2.4g/day.
Children Dosage:
Not recommended.
TRANDATE Contraindications:
Asthma. 2nd- or 3rd-degree AV block. Overt cardiac failure. Cardiogenic shock. Severe bradycardia, other conditions associated with prolonged or severe hypotension.
TRANDATE Warnings/Precautions:
Ischemic heart disease or failure. Monitor hepatic function; discontinue at first sign of liver injury. COPD. Pheochromocytoma. Diabetes. Surgery. Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers.
TRANDATE Classification:
Noncardioselective beta-blocker/alpha-1 blocker.
TRANDATE Interactions:
Caution with verapamil. Potentiates hypotension with nitroglycerin. May block epinephrine, β-agonist bronchodilators. Adjust antidiabetic medication. Potentiated by cimetidine. Tremor with tricyclic antidepressants. Halothane.
Adverse Reactions:
Dizziness, GI upset, fatigue, nasal stuffiness, ejaculation failure, headache, dyspnea, vertigo, rash, orthostatic hypotension, edema, heart failure, bronchospasm, jaundice.
How Supplied:
Tabs—100, 500
