Indications for: TWINRIX

Hepatitis A and hepatitis B immunization.

Adult Dosage:

≥18yrs: 1 inj IM in deltoid area at 0-, 1-, and 6 months. Alternate 4-dose schedule: 1 inj IM in deltoid area at 0-, 7-, and 21 to 30-days followed by booster dose at month 12.

Children Dosage:

<18yrs: not recommended.

TWINRIX Warnings/Precautions:

May defer in acute febrile illness or active infection. Bleeding disorders. Thrombocytopenia. Immunodeficiency: may get suboptimal response. Have epinephrine (1:1000) inj available. If given with immune globulin, use separate syringe and different site. Pregnancy (Cat.C). Nursing mothers.

TWINRIX Interactions:

Immunosuppressives may reduce efficacy.

Adverse Reactions:

Inj site reactions, headache, fatigue, GI upset, fever.


Register pregnant patients exposed to Twinrix by calling (888) 452-9622. Report adverse events to VAERS by calling (800) 822-7967.

How Supplied:

Single-dose vials—1, 10; Single-dose prefilled syringes—5