Benign prostatic hyperplasia/urinary retention:
Indications for: UROXATRAL
Benign prostatic hyperplasia (BPH).
Limitations of Use:
Not for use in children or for the treatment of hypertension.
Adult Dosage:
Swallow whole. Take immediately after same meal each day. 10mg once daily.
Children Dosage:
Not applicable.
UROXATRAL Contraindications:
Concomitant potent CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir). Moderate or severe hepatic impairment.
UROXATRAL Warnings/Precautions:
Not for use in women. Discontinue if angina develops or worsens. Severe renal insufficiency (CrCl <30mL/min). Hypotension. Mild hepatic impairment. History of QT interval prolongation. Exclude prostate cancer prior to initiation. Cataract surgery (intraoperative floppy iris syndrome possible).
UROXATRAL Classification:
Alpha-1 blocker.
UROXATRAL Interactions:
See Contraindications. Do not use with other α-blockers. Increased hypotension with concomitant nitrates, PDE5 inhibitors, other antihypertensives. Potentiates and is potentiated by cimetidine. Potentiates cardiovascular effects of atenolol. Caution with drugs that prolong QT interval.
Adverse Reactions:
Dizziness, upper respiratory tract infection, headache, fatigue; postural hypotension, syncope; rare: priapism.
How Supplied:
Tabs—30, 100
