Hyperacidity, GERD, and ulcers:

Indications for ZEGERID OTC:

Frequent heartburn (≥2 days/week). Not intended for immediate relief of heartburn (may take 1–4 days for full effect).


Swallow whole. Take at least 1 hour before eating in the AM. ≥18yrs: one capsule daily for 14 days; may repeat 14-day course every 4 months.


<18yrs: not recommended.


Trouble or pain swallowing food. Vomiting with blood. Bloody or black stools.


Heartburn >3 months. Chest or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck, or shoulders; or lightheadedness. Wheezing. Unexplained weight loss. Nausea/vomiting. Stomach pain. Sodium-restricted diets. Discontinue and reevaluate if condition continues or worsens after 14 days, require >1 course of treatment every 4 months; diarrhea, rash, or joint pain develops. Pregnancy. Nursing mothers.

Pharmacologic Class:

Proton pump inhibitor + antacid.


May affect or be affected by blood-thinning agents (eg, warfarin, clopidogrel, cilostazol), antifungals, digoxin, diazepam, tacrolimus, mycophenolate mofetil, antiretrovirals, methotrexate.

Adverse Reactions:


Generic Availability:


How Supplied:

Caps—14, 28, 42

Pricing for ZEGERID OTC

20mg/1100mg capsule (Qty: 42)
Appx. price $15