Imaging-Related Cancer Risk Low in Kids With Heart Disease

Share this content:
Imaging-Related Cancer Risk Low in Kids With Heart Disease
Imaging-Related Cancer Risk Low in Kids With Heart Disease

(HealthDay News) -- The lifetime risk of cancer attributed to radiation exposure in children with heart disease is low, according to research published online in Circulation.

Jason N. Johnson, MD, MHS, of the Duke University Medical Center in Durham, N.C., and colleagues evaluated the cumulative effective dose of radiation in 337 children with heart disease aged 6 years or younger. 

The authors sought to assess the lifetime attributable risk of cancer from imaging procedures. The children had undergone one of seven primary surgical procedures for heart disease.

RELATED: Use of CT Scans in Children: Is it Worth the Risk?

The researchers found that the most common radiation examination the children received was conventional radiographs (92%). The majority of cumulative exposure to radiation (81%) was attributed to cardiac catheterization and computed tomography. 

The overall associated lifetime attributable risk of cancer among the children was 0.07% (range, 0.001% to 6.5%). The median lifetime attributable risk of cancer varied widely according to the complexity of the surgical procedure performed (0.006% to 1.6%) and was twice as high per unit exposure in females versus males.

"To reduce long-term cancer risk, providers should target reducing radiation exposure in the highest-risk cohorts, including those children who will require repetitive high-exposure imaging and females because of their increased cancer risk," the researchers wrote.


  1. Johnson JN, Hornik C, Li JS et al. Cumulative Radiation Exposure and Cancer Risk Estimation in Children with Heart Disease. Circulation. 2014;doi:10.1161/​CIRCULATIONAHA.113.005425.

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs