New Lazanda Dose Available for Breakthrough Cancer Pain

Share this content:
Lazanda is now available at a 300 mcg dose strength to treat breakthrough cancer pain.
Lazanda is now available at a 300 mcg dose strength to treat breakthrough cancer pain.

Lazanda (transmucosal immediate release fentanyl [TIRF]) is now available at a 300 mcg dose strength to treat breakthrough cancer pain, Depomed has announced. This new dose will provide physicians with another titration option to improve dosing flexibility, so that patients can receive the appropriate dose for better pain management. 1

Lazanda is the only TIRF approved by the U.S. Food and Drug Administration that is delivered nasally. It is a fast-acting opioid agonist for patients who struggle swallowing due to nausea, or who experience vomiting, mucositis, oral ulcers, or dry mouth. Lazanda is  indicated only for adult patients who are already receiving and who are tolerant to opioid therapy for their underlying persistent cancer pain.

In addition to the new 300 mcg dose, Lazanda is available at 100 mcg and 400 mcg strengths. All patients should initially receive a single 100 mcg spray of Lazanda, which can be titrated up to a maximum of 800 mcg depending, on the achievement of adequate analgesia.

"Helping people living with chronic and acute pain is at the forefront of everything that we do," said Srinivas Rao, MD, PhD, Depomed's Chief Medical Officer. "We heard from health care providers about the need for greater dosing flexibility and are pleased that we were able to meet that need with a new dose strength for Lazanda. Depomed is committed to offering medications at strengths and formulations to best address the needs of people with pain."

RELATED: Low-dose Morphine More Effective in Treating Moderate Cancer Pain

Clinicians should be aware that Lazanda is available only through the TIRF REMS Access program, a restricted program that requires healthcare professional enrollment to prescribe Lazanda to outpatients and pharmacies.

Reference

1. Depomed releases Lazanda 300 mcg dose for treatment of breakthrough cancer pain [news release]. Newark, CA: Depomed; July 7, 2016. http://www.prnewswire.com/news-releases/depomed-releases-lazanda-300-mcg-dose-for-treatment-of-breakthrough-cancer-pain-300295134.html. Accessed July 8, 2016.

Related Resources

You must be a registered member of Cancer Therapy Advisor to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Prostate Cancer Regimens Drugs
Rare Cancers Regimens
Renal Cell Carcinoma Regimens Drugs
Skin Cancer Regimens Drugs
Urologic Cancers Regimens Drugs