General Oncology

Vigorous Exercise Improved Life Expectancy for Adult Survivors of Childhood Cancers

Vigorous Exercise Improved Life Expectancy for Adult Survivors of Childhood Cancers

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Researchers report on a retrospective cohort analysis that evaluated the long-term effects of vigorous exercise for survivors of childhood cancer.

Understanding Telomerase: Higher Quality Images Give Insight Into Developing New Agents for Inhibition

Understanding Telomerase: Higher Quality Images Give Insight Into Developing New Agents for Inhibition

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Telomerase plays a crucial role in tumor proliferation, and a better understanding of its structure will pave the way for new drug development.

Coffee and Cancer

Coffee and Cancer

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Several meta-analyses suggest that coffee consumption may decrease the risk of many types of cancers, but for some cancers, the data remain mixed or indicate an increased risk.

Risk of Diabetes May Increase After Cancer Diagnosis

Risk of Diabetes May Increase After Cancer Diagnosis

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Many studies have suggested that diabetes is a risk factor for the development of cancer, but whether or not cancer itself can increase the risk of diabetes requires further investigation.

Efficacy and Hyperemesis Syndrome Associated With Cannabinoid Use in Cancers ― In the Clinic

Efficacy and Hyperemesis Syndrome Associated With Cannabinoid Use in Cancers ― In the Clinic

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Many clinical trials and systematic reviews note that the use of cannabinoids also comes with adverse events, including a clinical entity that has been gaining evidence in the literature over the last decade called cannabinoid hyperemesis syndrome.

Achieving Long-Term Viral Suppression May Reduce Risk of AIDS-Related Cancers

Achieving Long-Term Viral Suppression May Reduce Risk of AIDS-Related Cancers

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Researchers hypothesized that ART, which suppresses viral load, improves immune function, and reduces inflammation, may lead to reduced cancer risk among HIV-positive patients.

IBM Watson Health Data Presented at ASCO 2018

IBM Watson Health Data Presented at ASCO 2018

Kyu Rhee, MD, MPP, discusses the latest updates at the ASCO 2018 meeting.

Latest Innovations in Value-Based Specialty Care

Latest Innovations in Value-Based Specialty Care

Charles Saunders, MD, speaks at the American Society of Clinical Oncology (ASCO) 2018 meeting in Chicago.

Investigational Studies on Lenvatinib, Pembrolizumab

Investigational Studies on Lenvatinib, Pembrolizumab

Josh Kremer, MD, discusses the latest research at the ASCO 2018 meeting.

Innovations in Engaging T-cells

Innovations in Engaging T-cells

Venkateshwar Reddy, MD, discusses research at the ASCO 2018 meeting.

President's Address at ASCO 2018 Emphasizes Growth, Delivery, Reach of Precision Medicine

President's Address at ASCO 2018 Emphasizes Growth, Delivery, Reach of Precision Medicine

With precision medicine nearly 23% of all patients who present with advanced lung cancer are treated with FDA- or EMA-approved targeted therapies or immunotherapies instead of chemotherapy.

Symptom Assessment Intervention Led by Lay Health Workers Improved Patient Satisfaction and Reduced Health Care Use and Costs

Symptom Assessment Intervention Led by Lay Health Workers Improved Patient Satisfaction and Reduced Health Care Use and Costs

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Lay health workers used phone calls to assess symptoms on a weekly basis for high-risk patients and on a monthly basis for low-risk patients.

Mobile Technology Is Useful in Collecting Patient-Reported Outcomes

Mobile Technology Is Useful in Collecting Patient-Reported Outcomes

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The researchers also developed novel emoji PRO scales and associations between PROs and wearable data.

Acupuncture and Cancer

Acupuncture and Cancer

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Though the mechanisms of action of acupuncture are not well-understood and continue to be an area of research, hypotheses include changes in neurohormones and immunomodulation through cytokines.

Managing Chemotherapy- and Radiation Therapy-Induced Nausea and Vomiting

Managing Chemotherapy- and Radiation Therapy-Induced Nausea and Vomiting

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CINV and RINV are a frequent source of misery and distress for patients and ineffective emesis control has well-documented impacts on health-related quality of life.

Oral Mucositis: Chemotherapy-Associated Toxicity

Oral Mucositis: Chemotherapy-Associated Toxicity

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Patients who receive chemotherapy or radiation therapy are at risk for developing oral mucositis, which causes inflammatory and/or ulcerative lesions of the oral mucosa

Can Oncolytic Viruses Improve Immunotherapies?

Can Oncolytic Viruses Improve Immunotherapies?

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Emerging evidence shows that injecting tumors directly into one tumor can trigger systemic antitumor immunity and immune attacks on untreated tumors elsewhere in the body.

Cognitive Behavioral Therapy Compared With Acupuncture for Insomnia in Cancer Survivors

Cognitive Behavioral Therapy Compared With Acupuncture for Insomnia in Cancer Survivors

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Investigators sought to determine whether cognitive behavioral therapy or acupuncture was more effective in addressing insomnia in this population.

Amygdalin and Cancer

Amygdalin and Cancer

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While some in vitro data suggests anticancer activity, animal and in-human studies fail to show efficacy and the risk of cyanide toxicity make amygdalin not recommended for use.

Emetogenic Potential of Antineoplastic Agents

Chart of emetogenic potential of antineoplastic agents divided up by high risk, moderate risk, low risk, and minimal risk.

Palliative care consultation linked to reduced direct hospital costs

The current study was a meta-analysis of available data which evaluate the change in direct healthcare costs associated with early palliative care consultation.

Relative Survival for AYAs Comparable to General Population After 7 Years

Relative Survival for AYAs Comparable to General Population After 7 Years

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Survivorship plans for adolescent and young adult survivors need to consider the relative long-term survival for AYAs with certain cancers. Those with certain cancers may have excess long-term mortality.

Cannabis and Cancer

Cannabis and Cancer

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Cannabis and its synthetic cannabinoids have been studied for medicinal properties across multiple disease states.

Clonally Transmissible Cancers in Nature

Clonally Transmissible Cancers in Nature

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While a recent discovery of a series of communicable cancers has raised concerns, there has been no sign of readily transmittable cancer in people that could spread through a population the way the ones found in other species do.

Oncologists May Not Be Adequately Informed About Medical Marijuana

Oncologists May Not Be Adequately Informed About Medical Marijuana

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There is a lack of robust data regarding medical marijuana for oncologists to base clinical decisions and discussions with patients.

Essential Oils and Cancer

Essential Oils and Cancer

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In-human studies have evaluated the use of EOs in a supportive role, and though EOs appear to have some efficacy in this setting, larger studies are needed to confirm their effects.

Does Larotrectinib Offer New Hope to Children With TRK Fusion-Positive Solid Tumors?

Does Larotrectinib Offer New Hope to Children With TRK Fusion-Positive Solid Tumors?

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Because of the drug's promising safety and efficacy, the first child was treated on trial only 9 months after the first adult with a TRK fusion was treated.

Cascara and Cancer

Cascara and Cancer

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Cascara use is not recommended because there are insufficient data for establishing its safety, and there have been reports of liver injury with high doses.

The Hunt for Effective Anticancer Vaccines

The Hunt for Effective Anticancer Vaccines

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Researchers are hotly pursuing 2 distinct biological paths that show remarkable promise in the hunt for an effective anticancer vaccine.

Physical Activity Monitors May Accurately Predict Patient Performance Status

Physical Activity Monitors May Accurately Predict Patient Performance Status

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At study completion, 75% of surveyed patients reported a positive experience with the PAM.

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