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GLUCAGON
Diabetes
Miscellaneous diagnostic tests
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Drug Name:

GLUCAGON Rx

Generic Name and Formulations:
Glucagon (recombinant) 1mg/mL; lyophilized pwd for IM, IV, or SC inj after reconstitution.

Company:
Lilly, Eli and Company

Therapeutic Use:

Indications for GLUCAGON:

Severe hypoglycemia.

Adults and Children:

Give by IM, IV, or SC inj. <20kg: 0.5mg or 0.02–0.03mg/kg. ≥20kg: 1mg. May repeat in 15mins as needed.

Contraindications:

Pheochromocytoma.

Warnings/Precautions:

If ineffective, IV dextrose must be given. When patient responds, supplemental carbohydrate should be given (esp. children). Type 1 diabetics may be less responsive. History of insulinoma or pheochromocytoma. Insufficient glycogen stores (eg, starvation, adrenal insufficiency, chronic hypoglycemia); treat with glucose. Necrolytic migratory erythema (w. continuous infusion). Monitor serum potassium. Pregnancy. Nursing mothers.

Pharmacological Class:

Antihypoglycemic.

Adverse Reactions:

Nausea, vomiting, allergic reactions (eg, urticaria, respiratory distress, hypotension).

How Supplied:

Emergency kit (1mg)—1 (w. diluent)


Data provided by MPR.

Indications for GLUCAGON:

Diagnostic aid in the radiologic examination of the stomach, duodenum, small bowel, and colon when diminished intestinal motility would be advantageous.

Adult:

See full labeling. Give by IV or IM inj prior to procedure. Usual range 0.25-2mg once. Stomach: 0.5mg IV or 2mg IM once. Colon: Give 10mins prior to procedure; 2mg IM once.

Children:

Not established.

Contraindications:

Pheochromocytoma.

Warnings/Precautions:

History of insulinoma or pheochromocytoma. Monitor serum potassium. Pregnancy. Nursing mothers.

Pharmacological Class:

Antihypoglycemic.

Interactions:

Concomitant anticholinergics: not recommended.

Adverse Reactions:

Nausea, vomiting, allergic reactions (eg, urticaria, respiratory distress, hypotension).

How Supplied:

Emergency kit (1mg)—1 (w. diluent)


Data provided by MPR.

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