Head And Neck Cancer

Understanding Telomerase: Higher Quality Images Give Insight Into Developing New Agents for Inhibition

Understanding Telomerase: Higher Quality Images Give Insight Into Developing New Agents for Inhibition

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Telomerase plays a crucial role in tumor proliferation, and a better understanding of its structure will pave the way for new drug development.

Efficacy and Hyperemesis Syndrome Associated With Cannabinoid Use in Cancers ― In the Clinic

Efficacy and Hyperemesis Syndrome Associated With Cannabinoid Use in Cancers ― In the Clinic

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Many clinical trials and systematic reviews note that the use of cannabinoids also comes with adverse events, including a clinical entity that has been gaining evidence in the literature over the last decade called cannabinoid hyperemesis syndrome.

Nimotuzumab in Combination With Concurrent Radiotherapy and Cisplatin Is Active in Locally Advanced SCCHN

Nimotuzumab in Combination With Concurrent Radiotherapy and Cisplatin Is Active in Locally Advanced SCCHN

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Nimotuzumab in combination with concurrent radiotherapy and cisplatin provides significant clinical benefits in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN).

Women With Head and Neck Cancer Receive Less Treatment and Have Inferior Outcomes Compared With Men

Women With Head and Neck Cancer Receive Less Treatment and Have Inferior Outcomes Compared With Men

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When variables such as age and serious medical conditions were accounted for cancer versus non-cancer mortality was two times higher for women compared with men.

Immune-Related Adverse Events During Anti-PD-1 Therapy May Increase Survival in Head and Neck Cancer

Immune-Related Adverse Events During Anti-PD-1 Therapy May Increase Survival in Head and Neck Cancer

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It is believed that immune competence may modify anti-tumor response with anti-PD-1 therapy.

Quality-of-Life Outcomes for Pembrolizumab Compared With Standard of Care in Head and Neck Cancer

Quality-of-Life Outcomes for Pembrolizumab Compared With Standard of Care in Head and Neck Cancer

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Two year treatment with pembrolizumab prolonged overall survival compared with standard of care among patients with HNSCC, but the effects on quality of life require further elucidation.

Nivolumab Plus Cetuximab and Radiotherapy May Be a Safe Treatment Option in Head and Neck Cancer

Nivolumab Plus Cetuximab and Radiotherapy May Be a Safe Treatment Option in Head and Neck Cancer

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Researchers sought to determine if the addition of nivolumab to radiotherapy and chemotherapy could improve outcomes among this patient population.

Nivolumab Plus Stereotactic Body Radiotherapy Fails To Improve Outcomes in Head and Neck Cancer

Nivolumab Plus Stereotactic Body Radiotherapy Fails To Improve Outcomes in Head and Neck Cancer

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Although the addition of stereotactic body radiation therapy (SBRT) to nivolumab did not increase toxicity, it did not lead to any improvement in response rates or survival outcomes among patients with metastatic head and neck squamous cell carcinoma (HNSCC).

Can Oncolytic Viruses Improve Immunotherapies?

Can Oncolytic Viruses Improve Immunotherapies?

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Emerging evidence shows that injecting tumors directly into one tumor can trigger systemic antitumor immunity and immune attacks on untreated tumors elsewhere in the body.

CYCORE System May Improve Radiotherapy-Associated Symptoms in Head and Neck Cancer

CYCORE System May Improve Radiotherapy-Associated Symptoms in Head and Neck Cancer

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The CYCORE system may enable physicians to intervene at the early signs of dehydration and other radiotherapy-associated symptoms.

Head and Neck Cancers Treatment Regimens

Head and Neck Cancers Treatment Regimens

View detailed treatment regimens for head and neck cancers, with options such as cisplatin, cisplatin + radiotherapy, and more.

Noninvasive Exhaled Breath Test May Be Effective In Diagnosing Esophagogastric Cancers

Noninvasive Exhaled Breath Test May Be Effective In Diagnosing Esophagogastric Cancers

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Oesophagogastro duodenoscopy is a diagnostic procedure to diagnose esophagogastric cancer, but is highly invasive and expensive.

Clonally Transmissible Cancers in Nature

Clonally Transmissible Cancers in Nature

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While a recent discovery of a series of communicable cancers has raised concerns, there has been no sign of readily transmittable cancer in people that could spread through a population the way the ones found in other species do.

The Hunt for Effective Anticancer Vaccines

The Hunt for Effective Anticancer Vaccines

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Researchers are hotly pursuing 2 distinct biological paths that show remarkable promise in the hunt for an effective anticancer vaccine.

Perioperative Gabapentin May Improve Pain Management in Head and Neck Cancer

Perioperative Gabapentin May Improve Pain Management in Head and Neck Cancer

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The total morphine equivalents used were, however, not significantly different between arms.

ACA Decreased Non-Insurance Rates Among Patients With Head and Neck Cancer

ACA Decreased Non-Insurance Rates Among Patients With Head and Neck Cancer

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These findings were, however, significant only in states that expanded Medicaid eligibility.

SLNBs Feasible After Wide Local Excisions in Melanoma of the Head and Neck

SLNBs Feasible After Wide Local Excisions in Melanoma of the Head and Neck

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Sentinel nodes were accurately identified in all 30 patients who underwent WLE.

Acetaminophen May Decrease Opioid Use After Head and Neck Cancer Surgery

Acetaminophen May Decrease Opioid Use After Head and Neck Cancer Surgery

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The number of PCA attempts did not differ between treatment arms.

Adjuvant Chemoradiotherapy Improves 5-Year OS in Salivary Squamous Cell Carcinoma

Adjuvant Chemoradiotherapy Improves 5-Year OS in Salivary Squamous Cell Carcinoma

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Approximately 50% and 30% of patients with late- and early-stage disease, respectively, undergo surgery without adjuvant therapy.

Celecoxib Reduces Opioid Use After Surgery in Head and Neck Cancer

Celecoxib Reduces Opioid Use After Surgery in Head and Neck Cancer

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The mean total opioid morphine equivalent use in the celecoxib arm was 31.8 mg vs 45 mg in the control arm.

Adjuvant Radiation May Improve Survival in Head and Neck Cancer

Adjuvant Radiation May Improve Survival in Head and Neck Cancer

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The benefit of adjuvant radiotherapy in this setting was previously unestablished.

Check-Mate 141 Results: Nivolumab Improved OS in Patients With Recurrent or Metastatic Head and Neck Cancer

Check-Mate 141 Results: Nivolumab Improved OS in Patients With Recurrent or Metastatic Head and Neck Cancer

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Not all patients who received nivolumab, however, had improved PFS.

HIV-Associated Cancers: A Paradigm Shift?

HIV-Associated Cancers: A Paradigm Shift?

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Many HIV-associated cancers develop with the help of oncoviruses — some of which are sexually transmitted.

Anticancer Immunotherapy to Circumvent Tumor Resistance to Immune Checkpoint Inhibitors

Anticancer Immunotherapy to Circumvent Tumor Resistance to Immune Checkpoint Inhibitors

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Most tumors do not respond, or evolve resistance, to immune checkpoint inhibition. Now, researchers at Johns Hopkins have engineered a new class of cancer immunotherapy agents designed to short-circuit key mechanisms of tumors' disruption and evasion of immune system attack.

Phase 1 Trials: Therapy, Not Just Science

Phase 1 Trials: Therapy, Not Just Science

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Phase 1 trials should be considered therapeutic options for some patients.

Immunotherapy and the Risk of Myocarditis

Immunotherapy and the Risk of Myocarditis

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The risk should not discourage patients with cancer from taking these potentially life-extending therapies.

Can A Consortium of Hospitals Help To Reduce Drug Prices?

Can A Consortium of Hospitals Help To Reduce Drug Prices?

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To help curb drug prices, a consortium of hospital groups recently announced plans to form their own nonprofit drug company.

Vitamin D May Not Reduce Head and Neck Cancer Risk

Vitamin D May Not Reduce Head and Neck Cancer Risk

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Findings from previous studies regarding the protective effects of circulating 25OHD for HNC risk are conflicting.

Oropharyngeal Squamous Cell Carcinoma: A Rising Risk in White Men

Oropharyngeal Squamous Cell Carcinoma: A Rising Risk in White Men

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Of nearly 100,000 cases in the evaluated timeframe, 31% were OPSCCs and 69% were non-OP HNSCCs.

Larotrectinib: Promising for All TRK-Positive Tumors

Larotrectinib: Promising for All TRK-Positive Tumors

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Larotrectinib may have durable antitumor activity in patients with TRK fusion-positive cancers, regardless of tumor type.

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