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Evidence Grows Linking BIA-ALCL to Textured Surface of Some Breast Implants

Europe halts sales of textured breast implants as more studies demonstrate a link between this type of implant and the development of a rare lymphoma.

Is Real-World Evidence a Complement to Randomized Clinical Trials?

Use of real-world data has the potential to accelerate drug and device approvals in rare diseases and advance precision medicine initiatives.

Researchers Report Early Clinical Promise for Macrophage Checkpoint Blockade

A doublet immunotherapy regimen incorporating the investigational mAb Hu5F9-G4 shows clinical activity in patients with relapsed/refractory non-Hodgkin lymphoma.

Gene-Delivery Method Generates Immune Checkpoint Antibodies In Vivo

In mice, DNA-encoded plasmids generated sufficient in vivo expression of immune checkpoint antibody CTLA-4; DMabs may one day rival traditional mAbs.

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