The Untold Story of the Longest Persisting CAR-T Cells in CLL
A deep dive into how CAR-T cells evolved in 2 patients with chronic lymphocytic leukemia who have had the longest complete remissions to date.
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Study Calculates Incidence of Opportunistic Infections During Ibrutinib Therapy
A study reported the incidence of opportunistic infections during ibrutinib treatment for hematological malignancies and identified potential risk factors.
Prostate Cancer Recurrence Risk Higher With Extensive Positive Margins
In a study, just 12.1% of cases with focal positive surgical margins (PSM) experienced biochemical recurrence compared with 54.1% of those with extensive PSM.
SABR May Up Survival in Oligometastatic Cancers
New data from a phase 2 randomized trial suggest that stereotactic ablative radiotherapy to sites of metastases may prolong overall and progression-free survival.
Follicular Lymphoma With Extranodal Disease Only: When to Suspect Systemic Disease
Follicular lymphoma manifesting with skin involvement only is considered to be a more aggressive disease than PCFCL.
Private Insurers Pay 241 Percent of What Medicare Would Pay
Prices paid to hospitals for privately insured patients in 2017 averaged 241 percent of what Medicare would have paid.
Colorectal Cancer Incidence Increasing in Younger Adults
Colorectal cancer incidence is increasing among young adults in certain high-income countries.
Quitting Smoking Lowers Risk for Bladder Cancer Postmenopause
Among postmenopausal women, former smokers have a reduced risk for bladder cancer within the first 10 years of cessation.
PARP Inhibitor Did Not Increase SCLC Response to Immune Checkpoint Blockade
A preexisting CD8+ T-cell response may be predictive of benefit from checkpoint blockade in SCLC.
Percutaneous Ablation Appropriate for Localized Renal Tumors
Researchers report long-term follow-up results showing no significant difference in oncologic outcomes among partial nephrectomy, radiofrequency ablation, and cryoablation for cT1 renal tumors.
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