OAB Symptoms Increase With Longer BCG Therapy for NMIBC
Intravesical BCG therapy is effective in treating NMIBC, but it comes with side effects such as overactive bladder.
Bladder Cancer News
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Bladder Cancer News
Breast, Prostate Cancer Common in Patients With COVID-19 and Cancer History
For patients hospitalized with COVID-19, prostate cancer was the most common cancer type across all databases.
Robotic-Assisted Radical Cystectomy Safe, Feasible for Octogenarians
The benefits of robotic surgery may have a more pronounced effect in octogenarians, according to investigators.
Neoadjuvant Chemo May Improve Outcomes for MIBC of Variant Histology
Findings refute the notion that variant histology MIBC will not respond to neoadjuvant chemotherapy.
How to Prevent a Cyberattack from Derailing Cancer Care
Cyberattacks on health care organizations may not be fully preventable, but there are ways to limit their impact on cancer care.
Older Adults May Benefit From NAC Prior to UTUC Radical Surgery
Neoadjuvant chemotherapy prior to radical nephroureterectomy for upper tract urothelial carcinoma may improve pathologic outcomes regardless of age, new data suggest.
CKD Associated With Worse Radical Cystectomy Outcomes
Investigators report increased risks for adverse pathology and 90-day readmission.
dd-MVAC Regimen ‘Should Be Gold Standard’ for Muscle-Invasive Bladder Cancer
Dose-dense methotrexate plus vinblastine, doxorubicin, and cisplatin improved time to progression.
Primary Chemoablation for Low-Grade Intermediate-Risk NMIBC Promising
A mitomycin-containing reverse thermal gel could provide an alternative to repetitive surgeries for low-grade intermediate-risk NMIBC, according to investigators.
BCG for Bladder Cancer May Lower Alzheimer Disease Risk
The risk for alzheimer disease decreased with increased dosing of BCG.
Partial, Radical Cystectomy for MIBC Yield Similar Survival Outcomes
In addition to similar rates of overall survival, patients undergoing partial and radical cystectomy had comparable rates of upstaging to pT3-4 disease.
Kidney-Sparing Surgery Offers Effective Oncologic Control in High-Risk UTUC
In this small study, even patients with high-risk tumors appeared to benefit from nephron-sparing surgery.
Epigenetic Test May Rule Out High-Grade UTUC
If validated, the EpiCheck® assay may identify more patients who can safely delay or avoid nephroureterectomy.
Neoadjuvant Chemotherapy Underused for MIBC in Older Adults
Older age independently predicted significant 48% lower odds of the gold standard treatment of NAC and radical cystectomy.
Nadofaragene Firadenovec Shows Longer-Term Efficacy in BCG-Unresponsive NMIBC
Study results support an attempt at bladder preservation in patients with BCG-unresponsive nonmuscle-invasive bladder cancer.
Outcomes of BCG-Unresponsive NMIBC Characterized
In a small study, most BCG-unresponsive patients who were initially managed conservatively ultimately underwent cystectomy.
First-Line Immunotherapy, Chemotherapy for mUC of the Bladder Offer Similar Survival
Real-world data validate recently reported findings from clinical trials.
Opdivo Approved as Adjuvant Treatment for High-Risk Urothelial Carcinoma
The approval was based on data from the phase 3 CheckMate-274 trial which evaluated nivolumab as an adjuvant treatment in 699 adults who have undergone radical surgery for invasive urothelial carcinoma at high risk of recurrence.
FDA: No Approval for Bladder Cancer Drug Vicineum
Vicineum is an investigational locally administered recombinant fusion protein that targets EpCAM antigens on the surface of tumor cells to deliver Pseudomonas Exotoxin A.
Sacituzumab Govitecan Elicits Responses in Previously Treated Metastatic Urothelial Carcinoma
Sacituzumab govitecan produced responses in all subgroups of patients.
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