No Surgery in Nearly 11% of Localized UTUC Cases
In a study, median survival time was significantly shorter among patients managed nonsurgically rather than surgically for localized upper tract urothelial carcinoma.
Bladder Cancer News
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Bladder Cancer News
UTUC Recurrence Risk Lowered With Adjuvant Chemotherapy
Adjuvant chemotherapy given to patients following underwent radical surgery for locally advanced upper tract urothelial carcinoma was associated with a significantly decreased risk of tumor recurrence.
First-in-Class, Targeted Therapy Approved for Metastatic Bladder Cancer
The approval was supported by data from a phase 2 multicenter, open-label, single-arm trial (N=87) of patients with locally advanced or metastatic bladder cancer with FGFR3 or FGFR2 genetic alterations that had progressed following treatment with chemotherapy.
Bladder Cancer Risk Elevated in Statin Users
In a large population-based study in Sweden, statin users had significant 31% increased odds of nonmuscle-invasive bladder cancer compared with nonusers.
The Predictive Ability of a Cancer Subtype Ontology Assignment
The Cancer Subtype Ontology resource includes 840 different cancer subtypes, many of which are novel.
High Monocyte-to-Lymphocyte Ratio Predictive of OS in Advanced Gallbladder Cancer
A high monocyte-to-lymphocyte ratio and a high platelet-to-lymphocyte ratio were predictive of poor OS in patients with advanced gallbladder cancer treated with chemotherapy.
Adding Chemotherapy to Radiation Post-Radical Cystectomy Improves Survival in Urothelial Carcinoma
Postoperative radiation therapy with adjuvant chemotherapy prolonged disease-free survival and overall survival in patients with locally advanced urothelial carcinoma.
Radiation, Chemotherapy Not Beneficial in Localized Upper Tract Urothelial Carcinoma
In a study of patients receiving non-surgical treatment for localized upper tract urothelial carcinoma, radiation or chemotherapy provided no overall survival benefit.
Radical Cystectomy Superior to Trimodal Therapy for Muscle-Invasive Bladder Cancer
Trimodal therapy for patients with muscle-invasive bladder cancer is associated with worse cancer-specific and overall survival and higher costs compared with radical cystectomy.
Pembrolizumab Shows Promise for BCG-Unresponsive Bladder Cancer
Pembrolizumab, a PD-1 inhibitor, demonstrated antitumor activity in patients with high-risk BCG-unresponsive carcinoma in situ.
Bladder Cancer Response to Bacillus Calmette-Guérin May Be Linked to Urine Microbiome
New evidence suggests variation in the bacterial composition of urine is associated with response BCG among patients with non-muscle-invasive bladder cancer.
Post-Cystectomy Short-Term Complications Not Hiked by NAC
Researchers found no significant difference in 30-day postoperative complications between patients who received neoadjuvant chemotherapy and those who did not.
FCT Compared With GD for Muscle-Invasive Bladder Cancer
An established chemoradiation regimen is compared with gemcitabine and once-daily radiation in the selective bladder-sparing treatment of muscle-invasive bladder cancer.
Frailty Assessment May Benefit Patients Undergoing Radical Cystectomy
Older patients should be routinely assessed prior to radical cystectomy to guide both
preoperative and postoperative care.
ctDNA Helped Predict Response, Survival After Durvalumab in Lung, Bladder Cancer
Analyzing ctDNA following drug treatment could help identify nonresponders to immunotherapy.
MicroRNA Signature in Urine May Predict Presence of Bladder Cancer
Researchers found a microRNA signature in urine that can predict the presence of bladder cancer, advancing the idea of a noninvasive diagnostic test.
Role of miR-125a-5p Clarified in Bladder Cancer
Researchers clarified the role of miR-125a-5p in bladder cancer, showing that it inhibits bladder cancer progression by targeting oncogene FUT4.
Bladder Cancer Clinical Features Linked to EGFR and HER2 Expression
A retrospective study found EGFR and HER2 overexpression associated with clinical features, such as tumor stage and tumor recurrence, in bladder cancer tissue.
Bladder Cancer Risk Higher With Radiation Therapy for Prostate Cancer
In a recently published study, external beam radiation therapy for localized prostate cancer was associated with a 35% increased risk of bladder cancer compared with radical prostatectomy.
Bladder Cancer Surveillance Not Aligned With Risk: Study of VA Facilities
Patients at VA facilities with high-risk early-stage bladder cancer tend to have cystoscopic surveillance at frequencies similar to those with low-risk disease.
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