Convection-Enhanced Delivery of Topotecan Active in Glioblastoma
Chronic convection-enhanced delivery of topotecan was feasible and well tolerated in patients with recurrent glioblastoma.
Brain Cancer News
BRAIN CANCER ADVISOR
Brain Cancer News
Cancer-Related Mortality Tied to Residential Segregation
Residential racial and economic segregation across US counties is associated with higher cancer mortality, a study suggests.
Dendritic Cell Vaccine Improves Upon Standard Care for Glioblastoma
Adding an autologous tumor lysate-loaded dendritic cell vaccine to standard care improves survival in patients with glioblastoma, a phase 3 study suggests.
Pediatric Cancer Survivors Experience Premature Aging
Young adult survivors of pediatric cancer experience significant premature aging, a retrospective study suggests.
Most Phase 3 Trials of Newly Diagnosed Glioblastoma Show No Improvement in OS
Most recent phase 3 trials of patients with newly diagnosed glioblastoma have shown no significant improvement in overall survival with the experimental treatment.
Deaths on the Rise in Patients With Malignant Brain Tumors
Deaths among patients with primary malignant brain tumors are on the rise in the United States, data suggest.
Risk of COVID-19 and Poor Outcomes Not Increased Among Glioma Patients
Patients with glioma do not have an increased risk of SARS-CoV-2 infection or worse outcomes from COVID-19, a single-center study suggests.
Neuroophthalmological Late Effects Common in Pediatric/Adolescent Medulloblastoma
Children and adolescents with medulloblastoma frequently suffer from neuroophthalmological sequelae, a single-center study suggests.
Predicting Outcomes of Regorafenib in Patients With Recurrent Glioblastoma
Researchers say they have identified a molecular signature that can be used to predict outcomes of regorafenib treatment in patients with recurrent glioblastoma.
Women With Glioblastoma May Be More Likely to Benefit From Immunotherapy
Among glioblastoma patients, women may derive more benefit from immunotherapy than men, research suggests.
Data Show Similar Patterns of Relapse in Standard- and High-Risk Medulloblastoma
Patterns of relapse are similar in patients with standard-risk and high-risk medulloblastoma, a review suggests.
Some Patients With High-Grade Glioma Continue Using Opioids After Perioperative Period
Nearly a third of patients with high-grade glioma who were prescribed opioids after surgery continued to take them beyond the perioperative setting.
Novel Agent Plus Radiotherapy Shows Promise in MGMT-Unmethylated Glioblastoma
VAL-083 in combination with radiotherapy is safe and active in patients with newly diagnosed MGMT-unmethylated glioblastoma, a phase 2 trial suggests.
How to Help Patients Navigate the Disability Claims Process
There are several steps health care providers can take to help patients with CNS cancers navigate the disability application process.
Adding Interferon-α to Temozolomide Prolongs Survival in High-Grade Glioma
Adding interferon-α to adjuvant temozolomide can prolong overall survival in patients with high-grade glioma, a phase 3 trial suggests.
Intracranial Metastasis of Esthesioneuroblastoma May Occur 19 Years After Remission
Recurrence of esthesioneuroblastoma with non-contiguous intracranial metastasis is possible 19 years after remission, a review suggests.
Tovorafenib Elicits Responses in Young Patients With BRAF-Altered Low-Grade Glioma
Tovorafenib produced responses in young patients with progressive or recurrent BRAF-altered low-grade glioma in a phase 2 trial.
Sequence of Ondansetron and Rolapitant Does Not Impact Efficacy in Malignant Glioma
The sequence of treatment with rolapitant and ondansetron does not appear to impact chemoradiation-induced nausea and vomiting.
Palliative Care Consultations Underused, Happen Too Late in High-Grade Glioma
About 1 in 10 patients with high-grade glioma had a palliative care consultation before the end-of-life phase, researchers found.
COVID-19 Vaccination Should Not Interrupt ICI Therapy, Researchers Say
COVID-19 vaccination is safe for cancer patients receiving immune checkpoint inhibitors and should not interrupt therapy, according to researchers.
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