Slight Increase Reported in Lung Cancer, Brain Tumors With Wildfire Exposure
Individuals exposed to wildfire within 50 km of residential locations in the past 10 years had a slightly higher incidence of lung cancer and brain tumors.
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Brain Cancer News
Molecular Profiling Can Guide Treatment After Recurrence in Young Cancer Patients
Nearly 70% of patients had at least 1 potentially actionable therapeutic target.
Eponyms in Oncology: Li-Fraumeni Syndrome
This weekly series highlights eponyms in oncology. This week, we explore the history and namesakes of Li-Fraumeni syndrome.
Blood Biomarkers May Help ID Primary CNS Lymphoma, High-Grade Glioma
Systemic inflammatory biomarkers may be useful in the differential diagnosis of primary central nervous system lymphoma and high-grade glioma.
Temozolomide Bests Nivolumab in Glioblastoma With Unmethylated MGMT Promoter
Overall and progression-free survival were superior with temozolomide.
Bevacizumab Biosimilar Alymsys Gets FDA Approval
The approval was based on data demonstrating that the biosimilar product and the reference product were highly similar, and that there were no clinically meaningful differences between the agents.
Assay-Guided Therapy Improves Survival in High-Grade Glioma
Patients who received treatment selected by the ChemoID assay had superior progression-free survival and overall survival.
Cell Phone Use Does Not Increase the Risk of Brain Tumors, Study Suggests
Researchers found no increased risk of any brain tumors among cell phone users.
Lymphopenia Tied to Risk of Infection After Radiotherapy
Measuring lymphocytes during or after radiotherapy could provide useful information about infection risk, according to researchers.
Maternal BMI, Diabetes Linked to Risk of Cancer in Offspring
Maternal obesity and diabetes may increase the risk of cancer, particularly leukemia, in offspring.
Sex is Independent Predictor of Death in Patients With CNS Cancer
Young men had a higher risk of death after any brain tumor diagnosis.
Risk of Leptomeningeal Metastasis in Melanoma Linked to Anatomic, Surgical Factors
Researchers found that entry into the ventricle space during surgical resection elevated the risk of leptomeningeal disease in patients with melanoma brain metastases.
Maternal Hormonal Contraception, CNS Tumors Not Linked in Children
No significant association was seen between maternal hormonal contraception use and CNS tumors in children younger than 20 years.
HLA Variant May Predict Poor Outcomes of Immunotherapy in Cancer Patients
HLA-A*03 was associated with worse progression-free and overall survival.
Armodafinil Does Not Reduce Cancer-Related Fatigue in High-Grade Glioma
The proportion of patients who reported improvements in fatigue was similar across the treatment arms.
Dabrafenib Plus Trametinib Yields Responses in BRAF-Mutant Gliomas
Patients with low-grade and high-grade glioma achieved responses.
ONC201 Shows Clinical Efficacy in H3 K27M-Mutated Diffuse Midline Glioma
Among patients with a performance status of less than 80, 20.6% had an improvement in this metric.
Adding Nivolumab to Standard Care Does Not Improve Survival in Glioblastoma
The median PFS was 10.6 months in the nivolumab group and 10.3 months in the placebo group.
Neuro-Oncology Patient Satisfaction Maintained During COVID-19 Pandemic
Patient satisfaction scores before the pandemic were comparable to scores during the pandemic.
One-Third of Patients May Not Recover From TMZ-Induced Aplastic Anemia
Patients without hematologic recovery had an increased risk of febrile neutropenia, infection, hospitalization, and death.
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