A study on the effects of an aggressive and strategic treatment called “Leading Edge” radiosurgery offers hope to patients diagnosed with life-threatening brain cancer. The study identifies the pathways of invasion of malignant glioma cells and provides a map in which a treatment plan can be developed to prevent the spread of one of the most deadly forms of malignant tumor, Glioblastoma Multiforme (GBM). GBM currently has a median survival rate of about 16 months.

“The aim of this new “Leading Edge” approach is not to focus single-fraction Gamma Knife radiation on where the tumor started, but where the tumor is going,” said Christopher Duma, MD, FACS, Brain Tumor Program Director at Hoag Memorial Presbyterian in Newport Beach, California. “Everyone thinks a tumor grows like a snowball. This particular brain tumor is different than any tumor in the body. You can’t remove it like a tumor. It intermixes with normal brain tissues and spreads through the brain along the white matter pathways.”

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