Ogivri, a Biosimilar to Herceptin, Now Available in the US
A biosimilar is a biological product that is approved based on data demonstrating high similarity to an FDA-approved biological product (reference product).
Breast Cancer News
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Breast Cancer News
RSNA: Biennial Mammo Returns More Advanced-Stage Cancers
Annual mammography screening, used by most patients, yields smaller and less advanced cancers.
Testing for Genetic Variants Informed the Use of Cancer Risk Assessments
Genetic testing provided important information beyond personal and family history.
Endocrine Therapy Lowers QOL for Breast Cancer Patients
Effects of chemotherapy found to be more transient in comparison.
Physical Activity After Cancer Diagnosis Improves Survival
Findings seen among postmenopausal breast cancer patients regardless of activity level prediagnosis.
Cancer Screening Rates Lower Among Women With Diabetes
Rates for breast, cervical, colorectal cancer screening lower compared with women without diabetes.
Patient Simulation Project in Lung, Breast Cancers Points to Improvements in Quality of Care
Palliative care and end-of-life needs were not addressed for approximately 40% of simulated patients who would have been eligible for this approach.
Prediagnosis Exercise May Reduce CV Risk in Breast Cancer
Incidence of composite cardiovascular events decreased across increasing total MET hours/week.
CDK4/6 Inhibitor + AI Therapy is Effective in Both Older and Younger Women With Breast Cancer
Rates of grade 3/4 AEs and dose reductions/interruptions associated with CDK4/6 + AI therapy were higher in those 75 years and older compared with younger patients.
IHC Assays for PD-L1 Lack Concordance in Metastatic TNBC
An exploratory analysis showed that the VENTANA PD-L1 SP142 IHC assay had subpar concordance with 2 other PD-L1 IHC assays that are not approved for metastatic TNBC.
Breast Cancer Mortality Rate Continues to Decline in the U.S.
Pace of decline slowed from 1.9 percent during 1998 to 2011 to 1.3 percent during 2011 to 2017.
Additional Support for Benefit of 21-Gene Assay in Early-Stage Breast Cancer: A Subgroup Analysis of TAILORx
In TAILORx, 84% of patients with a high recurrence score were treated with chemotherapy containing a taxane and/or an anthracycline prior to endocrine therapy.
Palbociclib, Capecitabine Regimens Offer Similar Patient-Reported Quality-of-Life Outcomes in Metastatic HR-Positive Breast Cancer
Results of the YoungPearl study revealed that patient-reported QoL scores were high for palbociclib plus endocrine therapy.
Abemaciclib Plus Fulvestrant Improved Survival in Patients with HR+, HER2- Advanced Breast Cancer
Results of MONARCH-2 showed a statistically significant and clinically meaningful improvement in overall survival with abemaciclib plus fulvestrant.
Longer Follow-Up Continues to Support Similar Efficacy and Safety of Trastuzumab Biosimilar in Breast Cancer
At 3-year follow-up, the mean LVEF was over 60% in both study arms.
Promising Results for Targeted Methylation Sequencing in the Detection of Multiple Types of Cancer
The precision of the targeted methylation sequencing assay for localizing the cancer tissue of origin was reported to be 89%.
Pembrolizumab Does Not Prolong Survival Compared With Chemotherapy in Metastatic TNBC
Pembrolizumab monotherapy does not improve overall survival (OS) compared with single-agent chemotherapy among women with metastatic triple negative breast cancer (mTNBC).
Persistent Diastolic Function Decline Noted With Contemporary Breast Cancer
Investigators evaluated the impact doxorubicin and/or trastuzumab have on diastolic function and the association between diastolic function and systolic dysfunction.
Reading, Literacy Levels of Chemotherapy Educational Materials for Women With Breast Cancer Are Not Optimal
An evaluation of patient education materials on chemotherapy for breast cancer revealed that many do not meet NIH recommendations.
Higher Mortality Seen for Male Breast Cancer Patients
Clinical characteristics, undertreatment correlated with 63.3 percent excess mortality rate for men.
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