Many Perceive Lack of Choice in Receipt of RAI for Thyroid Cancer
Thyroid cancer patients who perceive no choice about radioactive iodine report lower decision satisfaction.
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Once-Weekly Exenatide Treatment Does Not Increase Risk for Medullary Thyroid Carcinoma
Treatment with once-weekly exenatide 2 mg does not increase serum calcitonin concentrations or the risk for medullary thyroid carcinoma.
Cumulative Risk for Thyroid Cancer After Initial Benign Thyroid Biopsy
Patients who initially received negative thyroid biopsy results might face higher cumulative risk of developing thyroid cancer than that projected in previous literature.
Lenvatinib Active in Rare Adenoid Cystic Carcinoma
Proactive management of toxicities will be key for optimization of therapy.
High Response Rate for Patients With High-Grade Neuroendocrine Cancer Receiving Dual Immune Checkpoint Blockade
In the DART study, no patients with low-grade neuroendocrine tumors achieved a response to the combination of nivolumab plus ipilimumab.
Vitiligo May Be Associated With Reduced Risk of Internal Cancer
Reductions in the risk of cancer were more pronounced in men and younger patients with vitiligo.
Molecular Testing May Prevent Unnecessary Treatment of Suspicious for Malignancy Thyroid Nodules
Molecular testing may identify benign disease in some patients with thyroid nodules classified as suspicious for malignancy, helping them avoid unnecessary treatment.
Lobectomy Rates for Low-Risk DTC Are Rising
Adherence to the 2015 recommendation from ATA — to use lobectomy rather than complete thyroidectomy for low-risk differentiated thyroid cancer — is increasing.
Childhood Radiation-Induced Thyroid Cancer Does Not Lower All-Cause Survival
Childhood radiation-induced thyroid cancer does not affect all-cause mortality compared with healthy individuals.
RET Inhibitor May Be Effective in RET-Altered Thyroid Cancers
RET inhibitor LOXO-292 was well tolerated and demonstrated high antitumor activity against RET-altered thyroid cancers.
Malignancy Rates Higher in Children With Indeterminate Thyroid Nodules
Malignancy was more common in children with thyroid nodules classified as indeterminate by BSRTC criteria compared with adults.
Investigators Pinpoint Immune-Related Genes That Are Upregulated in ATC and PTC
Immune-related gene sets, including those for PD-L1/L2, are upregulated in ATC and PTC, but not in poorly differentiated disease or normal tissue.
MEK1/2 Inhibitor After RAI Fails to Improve Outcomes in High-Risk Nonmetastatic Thyroid Cancer
The addition of selumetinib to radioactive iodine did not improve the complete remission rate among patients with high-risk nonmetastatic differentiated thyroid cancer.
Soluble PD-L1 Levels Associated With Disease-Free Survival in Papillary Thyroid Cancer
High serum soluble PD-L1 levels are associated with shorter disease-free survival among patients with papillary thyroid cancer.
Ethanol Sensitization May Improve RFA of Benign Thyroid Nodules
Ethanol sensitization before radiofrequency ablation of benign thyroid nodules reduced time, ablation energy, and complications compared with conventional ablation.
Recombinant Human Thyrotropin Use Has No Effect on Outcomes After Radioiodine in DTC
Outcomes after radioiodine therapy are similar after preparation with either recombinant human thyrotropin or thyroid hormone withdrawal.
PRRA Fails to Improve Long-Term Outcomes in Low-Risk Papillary Thyroid Cancer
Postoperative radioiodine remnant ablation did not improve long-term outcomes among patients with low-risk papillary thyroid carcinoma.
US Centers Fail to Analyze Neck Lymph Nodes in Preoperative Ultrasounds for Thyroid Cancer
Most imaging centers in the United States fail to analyze lateral neck lymph nodes during preoperative ultrasounds in patients with thyroid cancer.
BABA Robotic Thyroidectomy Determined to Be Safe and Effective
The BABA robotic thyroidectomy technique appears to be safe, with excellent outcomes in benign and malignant thyroid disease.
Effect of Neuroendocrine Tumor Classification Updates on Survival Rates in Pancreatic Cancer
Survival rates for pancreatic cancer should be stratified by disease subgroup to better reflect prognostic differences across the subgroups in this category.
Local Delivery of Cytotoxic Microparticles in Pancreatic Cancer
The local delivery of cancer medications, via microparticles, is being explored in pancreatic cancer.
First-Line Pembrolizumab Plus Chemoradiotherapy Found to Be Ineffective in Anaplastic Thyroid Cancer
Pembrolizumab plus chemoradiotherapy failed to improve survival and lead to unexpected deaths in a small study of patients with anaplastic thyroid cancer.
Thyroid irAEs Common With PD-L1 Inhibitors
Thyroid-based immune-related adverse events are common among patients treated with PD-L1 inhibitors.
TRK Inhibitor Effective in TRK-Fusion Advanced Thyroid Cancer
The TRK inhibitor larotrectinib was effective and well tolerated among patients with relapsed/refractory advanced TRK-fusion thyroid cancer.
Several Driver Genes, Tumor Suppressors Found to Be Mutated in Anaplastic Thyroid Cancer
Tumor suppressor and driver genes are frequently mutated in Korean patients with anaplastic thyroid cancer.
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