Keytruda Granted Full Approval for Advanced MSI-H or dMMR Solid Tumors
The conversion from accelerated approval to regular approval was based on data from the KEYNOTE-158 trial, the KEYNOTE-164 trial, and the KEYNOTE-051 trial.
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Endocrine Cancer News
Abortion Restrictions May Affect More than 20% of Pregnant Cancer Patients in the US
More than 20% of US patients diagnosed with cancer during pregnancy may be unable to terminate that pregnancy due to abortion laws in their state, a new study suggests.
Pentagon Study Finds Higher Cancer Rates Among Pilots, Ground Crews
Military pilots and the ground crews who fuel and maintain their aircraft have higher rates of certain cancers, a new study shows.
Adverse Birth Outcomes More Common Among AYAs With Cancer During Pregnancy
Adolescent and young adult patients diagnosed with cancer during pregnancy have a higher risk of adverse birth outcomes, a study suggests.
SBRT Well Tolerated, Effective for Primary Lung Neuroendocrine Tumor
SBRT should be offered as an alternative to surgical resection for patients with early-stage LNET, according to researchers.
Clonal Hematopoiesis More Prevalent in Pediatric Cancer Survivors
Survivors of pediatric cancer have a higher rate of clonal hematopoiesis than their peers at any age, a study suggests.
Nurse-Parent Collaboration Key to Successful 131I-MIBG Treatment for Neuroblastoma
Collaboration between parents and nurses is essential to the care of children with neuroblastoma receiving 131I-MIBG, a study suggests.
Second-Line Bevacizumab Provides No Benefit in Advanced Neuroendocrine Carcinoma
Adding bevacizumab to second-line chemotherapy does not improve survival in patients with advanced neuroendocrine carcinoma, a phase 2 study suggests.
AYAs With Hematologic Malignancies Have Higher Risk of Early Death
The risk of early death in AYAs with cancer depends on the type of malignancy they have as well as multiple demographic factors, a study suggests.
“One-Stop Shop” Screening Centers May Improve Cancer Detection
Centers that perform comprehensive cancer screening in a single appointment may enable earlier cancer diagnosis.
Many Thyroid Cancer Survivors Cite Inadequate Pretreatment Understanding
Many thyroid cancer survivors said they lacked understanding of their treatment before receiving it.
Patients With Neuroendocrine Tumors May Value QOL Over Survival
Many patients with advanced neuroendocrine tumors may value preserving their quality of life over extending their survival, a small study suggests.
Lifestyle May Counter Genetic Risk for Thyroid Cancer
The highest risk of thyroid cancer was seen in patients with both high genetic risk and an unfavorable lifestyle.
FDA Rejects Omburtamab for Neuroblastoma After Disappointing Panel Vote
Omburtamab is an investigational radiolabeled monoclonal antibody designed to target tumor cells that express B7-H3.
Cabozantinib Improves PFS in Radioiodine-Refractory Differentiated Thyroid Cancer
Cabozantinib prolongs progression-free survival in patients with previously treated radioiodine-refractory differentiated thyroid cancer, a phase 3 trial suggests.
Proton FLASH Radiotherapy Deemed Feasible, Comparable to Conventional Dose Rate Radiotherapy
Proton FLASH radiotherapy is feasible, safe, and provides pain relief for cancer patients with bone metastases, according to a first-in-human trial.
Treatment Changes May Have Reduced Rates of Invasive Breast Cancer in Childhood Cancer Survivors
The incidence of invasive breast cancer among childhood cancer survivors decreased from the 1970s to the 1990s.
Active Surveillance Feasible for Low-Risk Thyroid Cancer
Active surveillance may be a viable management strategy for most diagnosed thyroid cancers, according to researchers.
Donafenib May Be Alternative for Progressive, Advanced RAIR-DTC
Donafenib demonstrated efficacy in patients with progressive, locally advanced or metastatic radioactive iodine-refractory differentiated thyroid cancer.
177Lutetium-Octeotrate May Be Practice-Changing for Advanced Pancreatic Neuroendocrine Tumors
177Lutetium-octreotate can improve progression-free survival vs sunitinib in patients with progressive pancreatic neuroendocrine tumors.
Chemotherapy Doublets Remain Standard Care for Advanced Digestive Neuroendocrine Carcinoma
Etoposide plus cisplatin and irinotecan plus cisplatin remain the standard first-line chemotherapy options for advanced digestive neuroendocrine carcinoma, according to researchers.
Men Have Higher Risk of Cancer; Demographic and Lifestyle Factors Don’t Explain It
Men tend to have a higher risk of cancer than women, and factors such as smoking, alcohol use, and diet do not appear to explain this disparity.
Thyroid Cancer Often Detected in Asymptomatic Patients
Many thyroid cancers are discovered in patients who undergo surgery without thyroid-referable symptoms, an international study suggests.
Blood Type Linked to Outcomes of Immune Checkpoint Inhibitor Therapy in Metastatic Cancer
Blood type may influence response to immune checkpoint inhibitor therapy among patients with metastatic cancer, a study suggests.
US Is Home to More Than 18 Million Cancer Survivors
There were more than 18 million cancer survivors in the United States at the beginning of this year, according to new data.
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