ctDNA Testing in Colorectal Cancer Deemed Promising but Not Ready for Prime Time
Studies suggest that ctDNA testing has prognostic value in colorectal cancer, but more research is needed before it can be used in practice.
Gastrointestinal Cancers
GASTROINTESTINAL CANCER ADVISOR
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Risks of Second Primary Malignancies Increased in Colorectal Cancer Survivors
A systematic review and meta-analysis sought to determine the risk of second primary cancer for survivors of colorectal cancer. -
Liposomal Irinotecan Improves Upon 5-FU/LV in Refractory Pancreatic Cancer
Adding liposomal irinotecan to 5-fluorouracil and leucovorin can improve outcomes in gemcitabine-refractory, advanced pancreatic cancer, a phase 3 study suggests. -
Fruquintinib Potentially Practice-Changing in Refractory Metastatic Colorectal Cancer
Adding fruquintinib to best supportive care improved progression-free survival and overall survival in the FRESCO-2 trial. -
First-Line Pembrolizumab Failed to Improve PFS, OS in Advanced HCC
Adding pembrolizumab to lenvatinib does not improve outcomes in patients with advanced hepatocellular carcinoma, results of the LEAP-002 study suggest.
GASTROINTESTINAL CANCER NEWS
Red-Flag Signs and Symptoms of Early-Onset Colorectal Cancer
Adding Cixutumumab to Paclitaxel Does Not Improve Outcomes in Esophageal/GEJ Cancer
Cancer Death Rates Vary Across Congressional Districts
Participation in Cancer Screening Low for Those With Severe Mental Illness
High TMB Associated With Better Outcomes of ICI Therapy in Advanced Cancers
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