Not Developing Any New Drugs Could Be EQRx’s Biggest Innovation
The best bet for a new company hoping to deliver on a lofty promise to “remake medicine” could rely on drug repurposing.
Gastrointestinal Cancers News
GASTROINTESTINAL CANCER ADVISOR
Gastrointestinal Cancers News
“Medical Distancing” May Help Protect Cancer Patients From Exposure to COVID-19
Screening patients by phone before they come to a clinic may help to eliminate potentially redundant visits and lower the risk of infection.
Recurrence-Free and Overall Survival Better in Adult Patients With Colon Cancer
Patients older than 25 years have significantly higher rates of OS and RFS at 3 and 5 years compared with patients younger than 25.
Risk for Liver Cancer Down With Low-Dose Aspirin in Hepatitis B, C
Risk for 10-year liver-related mortality also lower among aspirin users with chronic hepatitis B or C.
First Human Clinical Trial in US to Test the Use of CRISPR-Modified T Cells in Cancer Answers Vital Questions
CRISPR-modified T cells were used in 3 patients with advanced cancer for the first time, showing modest results on tumor growth.
More Support for “Watch-and-Wait” Approach in Subgroup of Patients With Resectable Rectal Cancer
Suspected local disease regrowth was seen in 23% of patients with rectal cancer observed following a near or complete clinical response to neoadjuvant therapy.
Improving Cancer Pain Management Amid the Opioid Crisis
Research into opioid alternatives for cancer-related pain has stalled, however substance use disorders remain problematic.
Evidence Suggests B Cells Play a Role in Immunotherapy Response
New research shows that B cells — and not just T cells — influence whether patients respond to immunotherapy in melanoma, sarcoma, and kidney cancers.
The Questionable Practice That Permeates Oncology Clinical Trials
Most oncology phase 1 trials use a simplistic, outdated dose-finding technique, and experts agree that change is needed.
Bariatric Surgery May Cut Risk for Colorectal Cancer in Obese Patients
Relative risk for developing colorectal cancer reduced by about 35 percent with bariatric surgery for obesity.
Integrative Oncology: Using Evidence-Informed Medicine to Improve Patient Outcomes and Quality of Life
Lifestyle-based integrative treatment approaches — deemed scientifically sound by the field’s proponents — merge conventional and complementary treatments.
Adding Cetuximab to Chemotherapy Shortens Survival by 2 Years in Advanced CRC
Adding cetuximab to chemotherapy led to worse outcomes for patients with resectable liver metastases caused by colorectal cancer, updated data from the New EPOC trial showed.
Bariatric Surgery May Be Associated With a Higher Risk for Colon Cancer
Researchers concluded that bariatric surgery is strongly associated with an increased risk for colon cancer, though further research may be needed to establish an association between bariatric surgery and an increased risk for rectal cancer.
Circulating Insulin-Like Growth Factor 1 Levels Linked to Colorectal Cancer
The study researchers concluded that higher circulating levels of IGF1 were associated with a higher risk for colorectal cancer and that lifestyle, diet, and/or pharmacological interventions that target the IGF system may help reduce disease risk.
Following Helicobacter pylori Infection, Gastric Cancer Risk High
Individuals who are racial or ethnic minorities and individuals who are smokers experience significantly higher risks for gastric cancer following a diagnosis of Helicobacter pylori infection.
Collagenolytic Microbes Associated With a Western Diet May Promote Tumor Formation After Colorectal Surgery
A mechanism was identified through which a Western diet and antibiotic use may be able to promote tumorigenesis by colon cancer cells after curative resection.
H. pylori Eradication Cuts Gastric Cancer Risk in Those With Family History
Gastric cancer risk reduced among those with H. pylori infection plus first-degree relatives with gastric cancer.
Therapeutic Advancements Have Facilitated Surgery Optimization, ASCO Officials Report
ASCO outlined advances in oncology that were the most clinically meaningful or had the biggest scientific impact from October 2018 through September 2019.
Distal Ureteral Management Methods Compared in UTUC
Intravesical incision of the bladder cuff may be superior to other distal ureteral management techniques, according to investigators.
Steep Increase Seen in Incidence of CRC From Age 49 to 50 Years
Increases seen across the U.S., in men and women, in whites and blacks, for colon and rectal cancers.
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