Higher coffee intake may be associated with significantly reduced cancer recurrence and death in patients with stage 3 colon cancer, a new study published online ahead of print in the Journal of Clinical Oncology has shown.
For the study, a team led by researchers at Dana-Farber Cancer Institute in Boston, MA, examined the influence of coffee, nonherbal tea, and caffeine on cancer recurrence and mortality in patients with stage 3 colon cancer.
Researchers analyzed data from 953 patients with stage 3 colon cancer that reported dietary intake of caffeinated coffee, decaffeinated coffee, and nonherbal tea, among various other items, during and 6 months after adjuvant chemotherapy.
Results showed that patients drinking four or more cups of caffeinated or decaffeinated coffee per day have a 42% (HR = 0.58; 95% CI: 0.34, 0.99) reduced risk for colon cancer recurrence or mortality compared with those who never drink coffee (Ptrend=0.002).
Increasing coffee intake was also associated with a significant reduction in cancer recurrence or mortality (HR = 0.66; 95% CI: 0.47, 0.93;Ptrend=0.006).
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Researchers found that patients consuming four or more cups of caffeinated coffee per day had a 52% (HR = 0.48; 95% CI: 0.25, 0.91) reduced risk for cancer recurrence or death versus never drinkers (Ptrend=0.002).
The study demonstrated no association between nonherbal tea or decaffeinated coffee and patient outcome.
- Guercio BJ, Sato K, Niedzwiecki D, et al. Coffee intake, recurrence, and mortality in stage III colon cancer: results from CALGB 89803 (Alliance). J Clin Oncol. 2015. [epub ahead of print]. doi: 10.1200/JCO.2015.61.5062.