Given the trial’s high attrition rate and low intervention adherence, no definite conclusions can be made between yoga and the health-related quality of life in patients with colorectal cancer, according to an article published online in the journal Psycho-Oncology.
Participants in this study included 54 patients (mean age 68.3 ± 9.7 years) who were randomly assigned to a 10-week yoga intervention (90 minutes once weekly; mean attendance 5.3 ± 4.0 yoga classes) or a waitlist control group. Twenty-seven patients were randomized to both the yoga and control group (attrition rate 22.2% and 18.5%, respectively).
Results showed no significant differences in the Functional Assessment of Cancer Therapy—Colorectal (FACT-C) total score between the two groups, which measured disease-specific quality of life.
However, differences were observed between the two groups’ emotional well-being at week 22 (∆ = 1.59; 95% CI: 0.27, 2.90; P= 0.019), sleep disturbances at week 22 (∆ = −1.08; 95% CI: −2.13, −0.03; P=0.043), anxiety at week 10 (∆ = −1.14; 95% CI: −2.20, −0.09; P=0.043), and depression at week 10 (∆ = −1.34; 95% CI: −2.61, −0.8; P=0.038).
Furthermore, no serious adverse events were observed in the yoga intervention cohort, while liver metastases occurred in one patient in the control group.
Cramer, H., Pokhrel, B., Fester, C., Meier, B., Gass, F., Lauche, R., Eggleston, B., Walz, M., Michalsen, A., Kunz, R., Dobos, G., and Langhorst, J. (2015) A randomized controlled bicenter trial of yoga for patients with colorectal cancer. Psycho-Oncology, doi: 10.1002/pon.3927.