A team of scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) discovered that a protein named IL23A is part of our stomach’s defense against bacterial infection which leads to gastric cancer. This finding could potentially be used to combat the deadly disease.

The research group, led by Professor Yoshiaki Ito, Senior Principal Investigator at CSI Singapore, also showed that the production of IL23A by stomach cells requires the tumor suppressor gene, RUNX3, which is frequently silenced in gastric cancer. The novel study was first published online in the leading journal Cell Reports.

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