(HealthDay News) — Robotic liver resection (RLR) is associated with a significant reduction in perioperative morbidity, when compared with open liver resection (OLR), for the treatment of hepatocellular carcinoma (HCC), according to a study published in JAMA Surgery.

Researchers analyzed short- and long-term outcomes of 398 patients undergoing RLR or OLR for HCC from 5 Western high-volume centers (2010 to 2020). The analysis included 106 patients undergoing OLR who were matched to 106 patients undergoing RLR.

The RLR patients had a significantly longer operative time than OLR patients (median, 295 minutes vs 200 minutes; P <.001) but a significantly shorter hospital length of stay (median, 4 days vs 10 days; P <.001).


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RLR patients were less likely than OLR patients to be admitted to the intensive care unit (6.6% vs 19.8%; P =.002) or to have posthepatectomy liver failure (7.5% vs 28.3%; P =.001). There were no cases of grade C failure.

The 90-day overall survival rate was similar between the groups (99.1% for RLR and 97.1% for OLR), as was the cumulative incidence of death related to tumor recurrence (8.8% for RLR and 10.2% for OLR).

“RLR performed in tertiary centers represents a safe treatment strategy for patients with HCC and those with compromised liver function while achieving oncologic efficacy,” the authors wrote.

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