Researchers from the University of Barcelona (UB) have synthetized a compound proved to be a potent inducer of apoptosis in a broad spectrum of tumour cell lines. According to a study recently published in the scientific journal Angewandte Chemical International Edition, the new molecule targets prohibitin, a protein involved in different cell processes and diseases, particularly in tumoral processes. Results represent a promising new therapeutic strategy for cancer treatment and drug discovery.
Several UB research groups centred on different areas collaborated in the study, coordinated by Rodolfo Lavilla, lecturer from the Department of Pharmacology and Therapeutic Chemistry of UB; Joan Gil, professor from the Department of Physiological Sciences II and researcher at the Bellvitge Biomedical Research Institute (IDIBELL), and Fernando Albericio, professor from the Department of Organic Chemistry of UB and researcher at the Institute for Research in Biomedicine (IRB Barcelona).
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