The incidence of endometrial cancers is elevated for women across all racial/ethnic groups, while non-Hispanic black women have excess incidence of aggressive cancers and lower survival, according to a study published in Cancer Epidemiology, Biomarkers & Prevention.

Michele L. Cote, Ph.D., from Wayne State University in Detroit, and colleagues analyzed endometrial cancer incidence and mortality data from the Surveillance, Epidemiology, and End Results program from 2000 to 2011. 

They examined age-adjusted incidence and incidence-based mortality rates, as well as annual percent changes (APCs). Racial/ethnic groups were compared by calculating rate ratios.

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The researchers observed increasing incidence rates for endometrial cancers across all racial/ethnic groups, with the greatest APC seen for non-Hispanic black and Asian women (APC, 2.5 for both).

The incidence rates of aggressive endometrial cancers were significantly higher for non-Hispanic black versus non-Hispanic white women.

For all tumor subtypes, incidence rates for Hispanic and Asian women were equal to or lower than non-Hispanic white women.

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Compared with non-Hispanic white women, the five-year relative survival for non-Hispanic black women was significantly less for nearly every stage and subtype, while Hispanic and Asian women had the same or better survival.

“Endometrial cancer incidence is increasing for all women, particularly the aggressive subtypes,” the authors write.

“The disparity associated with excess incidence for these aggressive histologic subtypes and poorer survival is limited to non-Hispanic black women.”


  1. Cote ML, Ruterbusch JJ, Olson SH, et al. The Growing Burden of Endometrial Cancer: A Major Racial Disparity Affecting Black Women. Cancer Epidemiology, Biomarkers & Prevention. 2015. [epub ahead of print]. doi: 10.1158/1055-9965.EPI-15-0316.