Higher Risk of Ovarian Clear Cell Cancer in Asian Pacific Islanders
Regardless of birthplace, women who are Asian Pacific Islanders appear to have a higher risk of developing ovarian clear cell cancer compared with other ethnicities.
Gynecologic, Ovarian, and Cervical Cancer News
GYNECOLOGIC CANCER ADVISOR
CMS Covers Next-Generation Sequencing for Breast and Ovarian Cancer
CMS recently announced that patients with germline ovarian or breast cancer would be covered for diagnostic testing that uses next-generation sequencing.
ASCO Guideline: Germline Testing Recommended for All Women Diagnosed With Epithelial Ovarian Cancer
A pervading theme of this guideline was the importance of including genetic counselors in the interpretation and communication of germline and somatic testing results.
Whether HPV Vaccination Will Prevent Cervical Cancer Unclear
Review highlights limitations of trial design; additional research needed to address uncertainties.
Bevacizumab Adoption Tied to Use by Peers
The decision to adopt bevacizumab could be appraised by the prior level of uptake among their peers in their medical community.
Fertility-Sparing Surgery Achieves Good Oncologic, Obstetric Outcomes in Younger Women With Early-Stage Nonepithelial Ovarian Cancer
In this first reported prospective study, researchers compared outcomes of fertility-sparing surgery with radical surgery in women with stage I nonepithelial ovarian cancer.
PALB2 Linked to Increased Risk for Breast, Ovarian, and Pancreatic Cancer
Germline PALB2 pathogenic variants were associated with an increased risk of female or male breast cancer, as well as ovarian and pancreatic cancer.
Addition of Maintenance Olaparib Slows Advanced Ovarian Cancer
Benefit substantial for homologous-recombination deficiency positive tumors with, without BRCA mutations
Testing for Genetic Variants Informed the Use of Cancer Risk Assessments
Genetic testing provided important information beyond personal and family history.
Secondary Surgical Cytoreduction Not Superior in Ovarian Cancer
Addition of surgery prior to chemotherapy does not prolong overall survival in recurrent ovarian cancer.
Cancer Screening Rates Lower Among Women With Diabetes
Rates for breast, cervical, colorectal cancer screening lower compared with women without diabetes.
Addition of Bevacizumab to Anti–PD-1 Therapy Improved Response Rate in Recurrent Ovarian Cancer
There is interest in determining whether antiangiogenic therapies can act synergistically with checkpoint blockade in the setting of recurrent ovarian cancer.
Maintenance Olaparib Found to Provide a PFS Benefit in Advanced Ovarian Cancer
The benefit was seen in an all-comers population, according to the presenters at ESMO Congress 2019.
Oophorectomy More Effective Than Ultrasound Screening in Preventing BRCA1-Related Ovarian Cancer
Results of a prospective study comparing effectiveness of ultrasound screening and salpingo-oophorectomy in preventing ovarian cancer are presented.
Intrauterine Device Use May Reduce Incidence of Ovarian Cancer
Novel noncontraceptive benefit seen for all intrauterine devices.
Pain Associated With Quality of Life and Survival for Patients With Recurrent Ovarian Cancer
Researchers sought to analyze how pain management affects quality of life and overall survival for patients with recurrent ovarian cancer.
Psychologic Distress Linked to Cervical Cancer Mortality
Risk up with diagnosis of stress-related disorders or an occurrence of stressful life events around diagnosis.
Germline BRCA2 Mutations Linked to Pediatric Lymphomas
Survivors of NHL should be offered genetic counseling.
Black Women With Cervical Cancer Less Likely to Receive Brachytherapy
Black women with cervical cancer were less likely to receive brachytherapy and had poorer survival, suggesting brachytherapy may mediate survival outcomes.
Zejula Gets Priority Review for Late Stage Ovarian Cancer Indication
The sNDA is supported by data from the multicenter phase 2 QUADRA trial that evaluated the safety and activity of Zejula in 463 patients.
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