Avelumab Provides No Benefit as Frontline Therapy or Maintenance in Ovarian Cancer
Avelumab did not improve progression-free survival when given concurrently with chemotherapy or as maintenance.
Gynecologic, Ovarian, and Cervical Cancer News
GYNECOLOGIC CANCER ADVISOR
Updated Data Confirm Safety of Olaparib Maintenance in Advanced Ovarian Cancer
Most adverse events in the olaparib arm were manageable with supportive treatment or dose modifications.
Use of PARP Inhibitor Maintenance on the Rise in Platinum-Sensitive, Recurrent Ovarian Cancer
PARP inhibitor use increased regardless of BRCA mutation status.
Cervical Cancer Incidence Predicted to Decrease or Remain Stable in Many Countries
Researchers analyzed recent trends in cervical cancer incidence and mortality and made predictions for the next 15 years.
Radiomics ‘Not Ready for Prime Time’ in Endometrial Cancer
More research is needed before radiomics can be used in clinical practice, according to researchers.
Survival Disparities in Endometrial Cancer Persist Despite Equal Access to Care
Factors other than access may affect differences in survival, according to researchers.
Updated Screening Guidelines for 5 Cancer Types
An update on the available cancer screening guidelines, benefits/limitations, and risks for cervical, breast, prostate, colon, and lung cancers.
Results Support Individualized Dosing of Niraparib Maintenance in Ovarian Cancer
Individualized niraparib dosing should be considered standard practice, according to researchers.
Sentinel Lymph Node Mapping Is ‘Highly Sensitive’ in Early-Stage Cervical Cancer
Among patients with a higher risk of metastasis, sentinel lymph node mapping had a sensitivity of 96.3%.
TVUS ET Screening Misses More Cases of Endometrial Cancer in Black Women Than in White Women
The disparity is due to the greater prevalence of fibroids and nonendometrioid histologic type in Black women, according to researchers.
Novel Genetic Variants Are Associated With Increased Risk of Cervical Cancer
Genetic variations in the PAX8, CLPTM1L, and HLA genes were found to be associated with a high risk of developing cervical cancer.
Removing a Large Uterus via Minimally Invasive Surgery Linked to Local Recurrence of High-Grade Endometrial Cancer
The results raise concern about potential local tumor spill, according to researchers.
Avelumab Doesn’t Improve Survival in Platinum-Refractory Ovarian Cancer
There was no improvement in progression-free or overall survival.
Oral Contraceptives Lower Ovarian Cancer Risk in BRCA Carriers
Findings seen in BRCA1 and BRCA2 mutation carriers; reduction greater with longer duration of use in BRCA1 carriers.
Rucaparib Bests Standard of Care in BRCA-Mutated, Relapsed Ovarian Cancer
Rucaparib prolonged progression-free survival.
Benefit of Niraparib Maintenance May Extend Beyond First Progression in Ovarian Cancer
There was an improvement in second progression-free survival, but not overall survival, with niraparib.
Atezolizumab Does Not Prolong Progression-Free Survival in Newly Diagnosed, Advanced Ovarian Cancer
There was no benefit with atezolizumab, regardless of PD-L1 status.
MRI-Guided Brachytherapy Deemed Safe and Effective in Locally Advanced Cervical Cancer
Researchers observed a high rate of long-term local control with MRI-guided adaptive brachytherapy after chemoradiotherapy.
Carboplatin Monotherapy Proves Inferior to Standard Therapy in Vulnerable Older Patients With Ovarian Cancer
Progression-free and overall survival were inferior with single-agent carboplatin.
Most Women in Their Mid-60s May Need to Continue Cervical Cancer Screening
A minority of women met criteria to exit cervical cancer screening.
- Loading...
Loading...
Want to read more?
Please login or register first to view this content.
Next post in Gynecologic Cancer
Loading... 
Loading...