Nerve-sparing (NS) laparoscopic radical hysterectomy (LRH) impairs sexual function less than conventional LRH in cervical cancer patients, according to a study published in the Journal of Sexual Medicine.
Giorgio Bogani, MD, from the University of Insubria in Varese, Italy, and colleagues evaluated sexually active cervical cancer patients undergoing type C (class III) LRH (2004 to 2013). The authors sought to determine the impact of NS procedures on preoperative versus postoperative sexual function.
The researchers found that, of the 40 patients undergoing radical hysterectomy (20 conventional LRH vs. 20 NS-LRH), there were no differences in preoperative Female Sexual Function Index (FSFI) scores (P>0.05).
While postoperative FSFI scores were worse in both groups (P<0.001), patients undergoing NS-LRH had higher postoperative FSFI scores than patients undergoing conventional LRH (21.3 vs. 14.2; P=0.04).
Specific postoperative domain scores showed that desire, arousal, orgasm and pain scores were similar between groups (P>0.05), while patients undergoing NS-LRH experienced higher lubrication (3.4 vs. 1.7; P=0.02) and satisfaction (4.6 vs. 2.8; P=0.004) scores, compared to patients undergoing conventional LRH.
Survival outcomes were similar between the groups.
“The NS approach impairs sexual function less, minimizing the effects of radical surgery,” the researchers wrote.