Cardiovascular diseases are a common cause of death among survivors of Hodgkin lymphoma. To evaluate the prevalence of coronary artery disease (CAD) in this patient population, researchers evaluated 48 survivors of Hodgkin lymphoma who were treated with mediastinal irradiation and had been disease-free for 10 years using electrocardiogram, exercise testing, and computed tomographic coronary angiography (CTA). Results indicated that 20% of patients had significant CAD on CTA, which was considerably higher than the 7% expected abnormalities. Significant stenosis was found and subsequent revascularization was performed in 11%. The researchers concluded that this study suggests CTA screening may be beneficial for survivors of Hodgkin lymphoma, but requires examination in a larger cohort.
We investigated the role of computed tomographic coronary angiography (CTA) as a screening tool for coronary artery disease (CAD) in asymptomatic Hodgkin lymphoma survivors, and related CTA findings to exercise testing and subsequent interventions. Patients and methods Patients were eligible for this phase II study if at least 10 years disease-free and treated with mediastinal radiotherapy.