Nanatinostat Gets Orphan Drug Designation for EBV-Associated Cancers
The “Kick & Kill” platform is designed to treat viral-associated cancers and other serious diseases.
Lymphoma News
LYMPHOMA ADVISOR
Lymphoma News
Presence of Autoimmune Diseases May Increase Risk for Diffuse Large B Cell, Marginal Zone Lymphomas
The presence of rheumatologic conditions was also associated with variations in cancer site for both diffuse large B-cell lymphoma and marginal zone lymphoma.
Support for Multimodality Therapy in Some Patients With Follicular Lymphoma
Follicular lymphoma is classified into 3 histologic grades on the basis of the number of centroblasts per high-power field.
A Case of Intra-Abdominal Follicular Lymphoma Presenting as Heart Failure
Results of epidemiologic studies suggest that exposure to Agent Orange may be associated with an increased risk of non-Hodgkin lymphoma.
Two Measures Independently Predict for NHL in Patients With HIV
Both a high HIV viral load and a low CD4 level independently predict for the risk of NHL in patients who have HIV.
Contrast-Enhanced MRI Characterization of Brain Cancers
According to researchers, neovascularization is more common in glioblastoma, and extravasation is more common in primary CNS lymphoma.
Marginal Zone Lymphoma Presentation at Multiple Mucosal Sites May Be Linked to Poorer Outcomes
Poor prognostic factors for patients with EMZL include age greater than 70 years, advanced Ann Arbor stage, and elevated lactate dehydrogenase (LDH)
Molecular Characterization of Pediatric Follicular Lymphoma
Pediatric follicular lymphomas involve interactions in MAPK and G-protein protein receptor signaling pathways, according to new research.
“Real-World” Hospitalization Data on Patients Receiving CAR-T Cell Therapy
An investigation of a large performance improvement clinical database revealed that most individuals receiving CAR-T have diagnoses of ALL or large B-cell lymphoma.
Overall Survival in Follicular Lymphoma With Complete Response Similar to General Population
Relative survival of patients with follicular lymphoma achieving a complete response (CR) at 30 months following initiation of immunochemotherapy was 100%.
SOX11 Status Not an Independent Prognostic Factor in Mantle Cell Lymphoma
Some distinct prognostic factors are observed for SOX11-negative compared with SOX11-positive mantle cell lymphoma.
Cure Rate Disparities Among Children With Burkitt Lymphoma
While the cure rate of children with Burkitt lymphoma is approximately 90% in higher-income countries, only 20%–70% of children with these diseases are cured in lower- or middle-income countries.
Textured Implants at Sites Other Than the Breast May Increase Risk of Implant-Associated ALCL
A case report describing the diagnosis of anaplastic large cell lymphoma (ALCL) in a woman who underwent cosmetic placement of bilateral, textured silicone gluteal implants was published online in Aesthetic Surgery Journal. 1 The US Food and Drug Administration (FDA) recently issued an update regarding the number of reported cases of breast implant-associated ALCL (BIA-ALCL), a rare form of…
Ambient Benzene Exposure and Risk of Hematologic Malignancies
Researchers examined low-level estimates of ambient benzene to investigate whether it was associated with increased cancer incidence across a nationwide cohort.
Ibrutinib Plus Nivolumab in 4 Cohorts of Patients With R/R NHL or CLL
According to results of an exploratory study, patients with Richter transformation may benefit from treatment with ibrutinib plus nivolumab.
Assessment of Treatment Intensity as a Predictor of Benefit in DLBCL
Patients with newly-diagnosed DLBCL receiving R-CHOP at or near full-dose intensity have improved overall survival, according to study authors.
A 5-Feature Radiomics Model to Predict Refractory Disease in Early-Stage Hodgkin Lymphoma
A study of the use of precision medicine-based “radiomic” features to evaluate risk of refractory disease in early-stage Hodgkin lymphoma showed promising results.
Low-Dose Lenalidomide Maintenance in Older Patients With PCNSL
Given the high likelihood of comorbidities and poor performance status in older patients with PCNSL, alternative treatment approaches are needed for this population of patients.
FDA Provides Update on Breast Implant-Associated Anaplastic Large Cell Lymphoma
The US FDA provided updated information to women with breast implants and their health care providers on the risk of developing a specific type of lymphoma.
NICE Recommends Use of Tisagenlecleucel for Adults With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Adults in the UK with R/R DLBCL and their health care providers now have the option of considering treatment with tisagenlecleucel, a CAR-T cell therapy.
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