Multiple Myeloma News
A team of investigators report on their validated nomogram that incorporates pleural effusion into the classification of disease severity in patients with multiple myeloma.
A retrospective, single-center crossover study was conducted that compared rates of infection in patients with multiple myeloma during observation compared with those receiving IVIG.
Researchers sought to determine whether adding daratumumab to standard care for patients with multiple myeloma was a cost-effective option.
Researchers sought to determine whether adding ixazomib to treatment with lenalidomide plus dexamethasone would give a benefit to patients with newly diagnosed multiple myeloma.
Researchers sought to determine whether cambinol would have antitumor activity in multiple myeloma cells.
Researchers compared clinical effectiveness and cost effectiveness of treatment regimens for multiple myeloma.
A workshop was convened by the US Food and Drug Administration and the American Association for Cancer Research to create recommendations for trial design and later stages of drug development in multiple myeloma.
A single-arm, phase 2 trial was conducted to assess response to treatment with carfilzomib plus cyclophosphamide and dexamethasone among patients with relapsed/refractory multiple myeloma.
Researchers sought to determine whether paroxysmal nocturnal hemoglobinuria clones might predict treatment responses for patients with MDS and aplastic anemia.
Ajai Chari, MD, of Mount Sinai Hospital in New York City, provides his perspective on the current state of care in multiple myeloma.
The approval is supported by data from the multicenter, randomized, open-label phase 3 IKEMA trial.
Semistructured interviews of patients and clinicians were conducted to explore how this disease affects the day-to-day lives of patients.
Abecma is a B-cell maturation antigen (BCMA)-directed genetically modified autologous T cell immunotherapy.
Progression-free, three-year overall survival similar for lenalidomide maintenance regimen without dexamethasone.
A team of investigators sought to improve the rates of anticoagulation for high-risk patients after a quality improvement project that added pharmacy/hematology oversight to VTE risk assessment.
A retrospective analysis sought to determine the effect of omitting premedications and use of a rapid infusion rate on infusion-related reactions in patients receiving daratumumab for multiple myeloma.
For patients with IgA multiple myeloma, monitoring disease progression with quantitative IgA may be superior to the conventional approach.
The phase 2 MagnetisMM-3 trial will test the safety and efficacy of subcutaneous elranatamab (PF-06863135) for relapsed or refractory multiple myeloma.
Researchers sought to confirm the efficacy and safety of 3 target doses of this B-cell maturation antigen-directed CAR-T therapy.
Cartesian Therapeutics launches a trial of Descartes-11, which is designed to express CAR-T molecules transiently.