Napabucasin Provides No Added Benefit in Metastatic Pancreatic Cancer
The phase 3 CanStem111P study was terminated early due to futility.
Pancreatic Cancer News
PANCREATIC CANCER ADVISOR
Pancreatic Cancer News
Rucaparib Maintenance Deemed Safe, Effective for Advanced Pancreatic Cancer
Rucaparib was active in patients with germline BRCA2, germline PALB2, and somatic BRCA2 variants.
Minority Patients Remain Underrepresented in Clinical Trials of Pancreatic Cancer
Non-White and non-Hispanic patients were underrepresented throughout the period studied.
SBRT Plus Pembrolizumab and Trametinib Confers Survival Benefits in Pancreatic Cancer
Stereotactic body radiotherapy plus pembrolizumab and trametinib improved overall and progression-free survival.
Changes in Clinical Trial Conduct Prompted by the COVID-19 Pandemic Should Persist
The AACR COVID-19 and Cancer Task Force recommends keeping changes to clinical trial practices that were prompted by the pandemic.
Study Supports Maintenance Over Sequential Treatment Strategy in Metastatic Pancreatic Cancer
A sequential treatment strategy was less effective than a maintenance strategy.
Adding Nab-Paclitaxel to Gemcitabine May Improve Overall Survival in Resected Pancreatic Cancer
Nab-paclitaxel was associated with an improvement in long-term overall survival.
ASCO and Friends: Cancer Patients Should Be Included in COVID-19 Vaccine Trials
A statement recommends including cancer patients and survivors in COVID-19 vaccine trials.
The Past, Present, and Future of GRASP: Connecting Cancer Researchers, Clinicians, and Patient Advocates
GRASP co-founder Julia Maués explains how the initiative came about and reveals plans for the future.
Age and Race May Determine Whether Cancer Patients Access Their Electronic Health Records
Black cancer patients were 44% less likely than White patients to enroll in a portal that provides access to electronic health records.
Hypofractionated A-RT After Chemotherapy Resulted in Locoregional Control in Pancreatic Cancer
The single-center study evaluated 119 consecutive patients with LAPC who underwent A-RT from 2016 to 2019.
Contrast-Enhanced vs Conventional Endoscopic Ultrasound for Diagnosis of Pancreatic Lesions
A team of investigators sought to investigate the usefulness of contrast-enhanced harmonic ultrasound-guided fine needle aspiration/biopsy when performed with no on-site cytopathology.
Pegilodecakin Plus FOLFOX Fails to Improve Outcomes in Metastatic PDAC
SEQUOIA trial investigators compared pegilodecakin plus FOLFOX with FOLFOX alone in patients with metastatic pancreatic ductal adenocarcinoma (PDAC).
Vitamin D and Pancreatic Cancer: is There a Link?
Vitamin D is a biomarker of interest in the pancreatic cancer setting.
American Cancer Society 2021 Statistics Report Shows Continuous Decline in Cancer Mortality Rate, Illuminates Disease-Specific Trends
The American Cancer Society’s annual report approximates the new cancer diagnoses and deaths expected in 2021 and identifies impactful patterns in oncology care.
PERT Shows Promise in Unresected Pancreatic Cancer
Investigators compared the outcomes of patients who received pancreatic enzyme replacement therapy (PERT) with those who did not.
CD73 Inhibitor-Based Triplet Induces Responses in Metastatic PDAC
The ARC-8 study evaluated whether AB680, the anti-PD-1 antibody zimberelimab, and chemotherapy could improve metastatic pancreatic adenocarcinoma (PDAC) outcomes.
Neoadjuvant Urelumab Plus Nivolumab and GVAX for Reresected Pancreatic Cancer
Preliminary data suggest that neoadjuvant treatment of resected pancreatic cancer with urelumab plus nivolumab and GVAX was well tolerated and showed some antitumor activity in a small study.
Targeted Therapies, Immunotherapies, Immunomodulators: A Quick Guide to Cancer Therapy Descriptions
Sometimes the distinctions between cancer treatment groups are a little blurry. Here’s a guide to their definitions and origins.
Reliability of Laboratory-Developed Tests Called Into Question
A recent HHS announcement spurred concern that FDA oversight of LDTs was eroding, threatening patient safety — but the reality is less dire.
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