Increased Mortality Risk in Patients With Cancer Experiencing the Death of a Child
Population-based study evaluated survival outcomes for patients with cancer diagnosed over a 41-year period.
Pediatric Cancer News
PEDIATRIC CANCER ADVISOR
Pediatric Cancer News
Evolving Incidence Trends in AYA Cancers
Cancer incidence trends across 41 countries demonstrated sharp increases and decreases in certain cancer types over the last 15 years.
Role Exists for Re-Irradiation of Older Patients with Recurrent Glioma
Survival from time of recurrence was similar to that seen in younger patients.
ctDNA Methylation May Identify Pediatric Medulloblastoma
Pediatric medulloblastoma demonstrated a distinct methylation profile that could identify the disease and monitor treatment response.
Extensive Molecular Characterization Uncovers Actionable Alterations in Many High-Risk Pediatric Cancers
As part of the Zero Childhood Cancer Program, high-risk pediatric tumors were characterized by whole-genome sequencing, RNA sequencing, and methylation profiling.
First-Ever Prospective Trial in Pediatric RCC Reports Results
The prospective study showed that after 4 years, complete resection of the tumor for children with local lymph node involvement (no metastasis) delivered an overall survival rate of 91.4%.
FDA, EMA Call for Coordinated Submission of Plans to Study Pediatric Cancers
The FDA and EMA expressed the need for trial sponsors to coordinate their submissions of initial pediatric study plans and pediatric investigation plans for new oncology drugs.
Cancer Incidence Up for Adolescents and Young Adults
2007 to 2016 saw increase in overall cancer incidence in all age groups, mainly driven by thyroid cancer.
Hearing Loss Associated With Neurocognitive Deficits in Pediatric Cancer Survivors, Study Finds
A large cross-sectional cohort study investigated the relationship between hearing loss and measures of neurocognition in survivors of childhood cancers.
Children With Cancer Not Experiencing as Severe COVID-19 as Initially Feared
Studies suggest that the majority of pediatric patients with cancer and COVID-19 experience mild disease — rather than severe disease — as a result of infection with the novel virus.
COVID-19 Morbidity in Pediatric Cancer Patients Found to Be Low
The risk of disease for children with cancer may be similar to the risk for children in the general population.
Fewer Children Enrolling in Pediatric Cancer Trials
Adolescent and young adult cancer patients underrepresented in clinical trials.
Prevalence, Risks, Outcomes Associated With Pediatric Hematology/Oncology Fellow Burnout
Burnout rates among pediatric hematology/oncology fellows may be influenced by less patient-centered care and less humanistic practice.
Pedmark Receives Priority Review for Prevention of Cisplatin-Induced Ototoxicity
The application is supported by data from 2 pivotal open-label, randomized phase 3 trials (SIOPEL 6 and ACCL0431), which compared the efficacy of sodium thiosulfate plus cisplatin to cisplatin alone for the prevention of cisplatin-induced hearing loss.
RACE for Children Act Could Substantially Increase Studies of Pediatric Cancer Drugs
An analysis of previously approved novel anticancer agents estimates that more than 78% would have met the RACE for Children Act criteria for pediatric testing.
Expert Opinion on Addressing Psychosocial Needs of Children Receiving CAR-T Therapy
The authors of this article emphasized the importance of actively involving a diverse group of interdisciplinary team members in the psychosocial care of these patients.
AAP Addresses Fertility Preservation for Children With Cancer
Medical and ethical considerations are discussed, including in cases of conflict between parent, child.
Coronary Artery Disease Risk Down in Survivors of Childhood Cancer
Risk for coronary artery disease significantly decreased for survivors with diagnosis in 80s, 90s versus 70s.
Next-Gen Sequencing Found to Predict Bloodstream Infections in Children
At 3 days before a bloodstream infection, mcfDNA sequencing correctly predicted 12 of the 16 observed episodes.
Fertility Treatment and Childhood Cancer Risk: What’s the Link?
Of all types of fertility treatment examined, the only one that significantly increased the risk of cancer in children was frozen embryo transfer.
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