Cycling may have no effect on PSA levels as previously thought, according to a small meta-analysis published in Prostate Cancer and Prostatic Diseases.

Canadian researchers led by Dishay Jiandani, MSc, of York University in Toronto looked at current literature in order to determine whether cycling activity had any effect on PSA in healthy men who were free of any prostatic conditions.

“Recent literature has suggested that bicycling may be associated with increases in serum PSA levels,” they noted. “We conducted a systematic review and meta-analysis of current literature in this field.”

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Six studies were included in their final review, with self-reported bicycling activity as well as pre- and post-change in PSA levels.

Two studies found that, following cycling activity, total PSA had increased from baseline by up to 3.3-fold. Free PSA increased in another study, while they observed no change in four studies. One study that compared PSA levels in professional cyclists to non-cyclists demonstrated no significant difference in PSA measurements between the two groups.

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The data from six studies was meta-analyzed and the researchers saw no significant increase in PSA associated with cycling from pre to post.

“The limited number of trials and the absence of randomized controlled trials limit the interpretation of our results,” the authors concluded. “Our study may have low statistical power to detect a difference in PSA.”


  1. Jiandani, D., et al. “The effect of bicycling on PSA levels: a systematic review and meta-analysis.” Prostate Cancer and Prostatic Diseases. doi:10.1038/pcan.2015.16. [epub ahead of print]. May 5, 2015.