(HealthDay News) — Multiparametric magnetic resonance imaging (MRI) is highly accurate for the detection of prostate cancer in patients with clinically low-risk cancer, particularly for cancers with larger volume and higher Gleason grade, according to a study published in the May issue of Radiology.

Jin Young Kim, MD, from Keimyung University in Daegu, South Korea, and colleagues examined 100 patients with clinically determined low-risk prostate cancer utilizing multiparametric MRI (T2 weighted, diffusion weighted, and dynamic contrast material enhanced) before prostatectomy. The images were compared to histopathologic examination.

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The researchers found that multiparametric MRI showed high diagnostic performance for the detection of cancer ≥0.5 cm³ with respect to cancer volume and Gleason grade. This diagnostic accuracy was significantly higher for cancers with a volume >1 cm³, compared those with a volume of 0.5 to 1 cm³ (87.7% vs. 82.6%; P = 0.02) and for cancers with Gleason grades of ≥7 versus grades ≤6 (89.2% vs. 80.6%; P = 0.01).

“Detection of prostate cancer in patients with clinically low-risk cancer with multiparametric [MRI] is highly accurate, and larger cancer volume and higher Gleason grade are associated with higher detection accuracy,” the researchers wrote.

Reference

  1. Kim JY, Kim SH, Kim YH, et al. Low-Risk Prostate Cancer: The Accuracy of Multiparametric MR Imaging for Detection. Radiology. 2014;doi:10.1148/radiol.13130801.