Prostate Cancer Upgrading on AS Linked to Perineural Invasion
The presence of perineural invasion in a prostate biopsy has important implications for active surveillance.
Prostate Cancer News
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Prostate Cancer News
Study: Confirmatory Prostate Biopsies Still Needed Despite Upfront MRI
New findings challenge recommendations from the European Association of Urology.
Higher Body Fat Linked to Higher Risk of Death From Prostate Cancer
Increases in waist-to-hip ratio, body mass index, waist circumference, and total body fat percentage were associated with increases in the risk of prostate cancer death.
Negative MRI in Active Surveillance Often Predicts Stable Prostate Cancer
Some patients with a negative mpMRI while on prostate cancer active surveillance may be able to defer biopsy, according to investigators.
Prostate Cancer Upgrading Risk in Active Surveillance Does Not Differ by Race
Active surveillance appears to be a safe treatment option for low- and very low-risk prostate cancer, regardless of race, according to investigators.
Metastatic Prostate Cancer Survival Improved in Wake of Treatment Advances
Following the approval of cabazitaxel in 2010, there are now an unprecedented number of life-prolonging therapies for men with metastatic disease.
Prostate, Bladder Cancer Care Delays Common During Pandemic
Study characterized patient-reported delays in care of prostate cancer and bladder cancer at the national level.
Prostate Cancer Grade Migration Documented
Grade group 1 prostate cancers declined as a proportion of all prostate cancers.
New Model Improves Life Expectancy Estimates in Prostate Cancer Population
A novel life expectancy calculator could allow for more personalized management of men with prostate cancer.
Trials Supporting Cancer Drug Approvals Lack Information on Gender
Of more than 100 studies used to support drug approvals, none reported information on the gender of participants.
Risk of Cancer-Specific Death May Remain Elevated for 30 Years
Patients with certain cancers have an increased risk of cancer-specific mortality that persists for 30 to 35 years after diagnosis.
Proton Beam Therapy Increasingly Used to Treat Cancers, Even When Evidence of Effectiveness Is Lacking
The use of proton beam therapy (PBT) increased between 2004 and 2018, particularly for cancers in which the effectiveness of PBT is still under investigation.
Orteronel Does Not Improve Overall Survival in Prostate Cancer
Orteronel is likely not effective when compared with recently approved agents, according to researchers.
BRCA1/2 Variants Associated With More Cancers Than Previously Thought
Researchers identified associations between pathogenic variants in BRCA1/2 and 7 cancers.
Benefit of Long-Term ADT Varies by Risk Group in Localized Prostate Cancer
There was no significant benefit with long-term ADT, but researchers said there was a “clinically relevant” benefit in patients with high-risk disease.
Prostate Cancer Biopsy, Diagnoses Down During the Pandemic
Between March 2020 and March 2021, the estimated number of missed prostate cancer diagnoses ranged from 97 cases to 573 cases.
TMB May Help Guide ICI Use in Metastatic Castration-Resistant Prostate Cancer
Immune checkpoint inhibitors were more effective than taxanes in patients with a high tumor mutational burden.
DXA Screening Rate Low Among Older Men Initiating ADT for Prostate Cancer
Study confirms the care gap in bone health management and fracture prevention among older men with prostate cancer receiving androgen deprivation therapy.
Depression, Anxiety Rates High With Androgen Deprivation Therapy for Prostate Cancer
An analysis revealed a link between treatment with androgen deprivation therapy and new diagnoses of incident depression and anxiety in men with prostate cancer.
Perineural Invasion Linked to Biochemical Recurrence After Prostatectomy
Patients with perineural invasion had a 4-fold higher risk of biochemical recurrence.
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