Renal Cell Carcinoma

RENAL CELL CARCINOMA ADVISOR

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FEATURED CONTENT

The FDA Approval Process Needs Refinement, Not a Total Overhaul

Even though overall drug development times have not changed, questions about the clinical benefit of the drugs that have been approved through expedited pathways are being raised.
How Durable Are Responses to Targeted Therapies Across Single-Arm Cancer Trials?

Drugs approved based on changes to surrogate biomarker levels may be subject to measurement bias, according to investigators.
Reporting Mechanisms for Conflict of Interest Disclosures in Medicine Need Standardization

ASCO officials examined the discrepancies in financial disclosures across platforms and call for a simplified system.
Popular Genetic Tests Miss Many Cancer-Associated Genetic Variants, Particularly in Ethnic Minorities

The chance of missing a disease-causing variant can be as high as 100% across some groups.
Why We Need to Change How We Look for Renal Cell Carcinoma Biomarkers

Proangiogenic or proimmunogenic genomic and transcriptomic signatures in the tumor microenvironment may have predictive value.

VIDEO SERIES

Tivozanib for RCC

Genitourinary Oncology: A Peek Over the Horizon

Immunotherapy of Renal Cell Carcinoma

Targeted Therapies for Renal Cell Carcinoma

Genetics and Heterogeneity

Genetic Predisposition to Kidney Cancers

Personalized Medicines for Kidney Cancers

Drugs in the Pipeline

Resistance to Therapy Among Kidney Cancers

Targeted Therapy

The Role of Neoadjuvant Tx

Sx Options – Ablative Techniques

Sx Options – Lymph Node

Sx Options – Cytoreductive Nephrectomy

TKIs – First-Line Therapy

TKIs – Second-Line Therapy

Biomarkers in RCC

The MET Pathway

Checkpoint Inhibitors

RENAL CELL CARCINOMA NEWS

An analysis by members of the FDA showed that time to treatment discontinuation may be a viable end point to assess drug efficacy in the postmarketing setting.

Bevacizumab Adoption Tied to Use by Peers

January 17, 2020

Hepatitis C virus / Science Source

No Link Found Between Hepatitis C Infection and Extrahepatic Cancers

January 14, 2020

Updated Recommendations Issued for Treating Advanced RCC

December 30, 2019

Upfront NGS saves time and money compared with the sequential use of individual gene tests for patients with metastatic lung cancer, according to study authors.

High-Throughput Multichain Immune Repertoire Sequencing for Prediction of Treatment Response in Renal Cell Carcinoma

November 14, 2019

Baseline and changed neutrophil to lymphocyte ratio predict targeted treatment responses in mRCC.

Machine-Based CT May Help Identify BAP1 Mutation Status in Clear Cell Renal Cell Carcinoma

October 28, 2019

Next post in Renal Cell Carcinoma

kidney cross section

Getting More Specific About Adjuvant Therapy Effects in Kidney Cancer