The already approved antimicrobial drug pentamidine may be effective in treating renal cell carcinoma (RCC), or kidney cancer, according to new research published in Molecular Cancer Therapeutics. The study, which matched RCC gene expression patterns from patients with gene expression changes produced by commonly used drugs, showed in animal models that pentamidine decreased tumor growth and improved survival. Because repurposing currently used drugs is less expensive and requires less time for development and testing, these results are important to the prompt discovery of a potential new treatment for RCC.
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Renal Cell Carcinoma Patient with Liver Mets
By: Paul Bowlin, MD; E. David Crawford, MDA 72-year-old male presents with fatigue and shortness of breath. On initial laboratory evaluation, he is found to have a hematocrit level of 55%. His past medical history is significant for hypertension, hyperlipidemia,…
Antimicrobial Drug May Help Treat RCC
Developing and testing a new anti-cancer drug can cost billions of dollars and take many years of research. Finding an effective anti-cancer medication from the pool of drugs already approved for the treatment of other medical conditions could cut a considerable amount of time and money from the …