The incidence of Kaposi sarcoma is increasing among Black men in the United States, according to research published in JNCI Cancer Spectrum.

The study also showed a significant decrease in Kaposi sarcoma incidence among White men and a non-significant decrease among Hispanic men.

This study included data from 3838 men with Kaposi sarcoma who were 20 to 34 years of age. The patients were included in the National Program of Cancer Registries and the Surveillance, Epidemiology, and End Results Program Database.

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During the 2001-2018 time period, the largest percentage of Kaposi sarcoma cases were diagnosed in non-Hispanic Black men (46.0%), followed by Hispanic men (25.1%), non-Hispanic White men (24.1%), and other races (3.0%). 

The incidence of Kaposi sarcoma increased by 1.5% per year among non-Hispanic Black men. The incidence decreased by 3.5% per year among non-Hispanic White men and by 1.3% per year among Hispanic men. 

The rising incidence of Kaposi sarcoma among Black men was primarily attributed to a 3.3% per year increase in the South. 

The researchers postulated that the increasing Kaposi sarcoma incidence is likely attributable to increasing exposure to risk factors, including HIV infection, among non-Hispanic Black men who were born recently in the South.

The researchers found that Black men born in 1994 had a roughly 2-fold higher risk of Kaposi sarcoma than Black men born in 1979 in the South (incidence risk ratio, 2.2; 95% CI, 1.5-3.3).

“Targeted HIV prevention and treatment in young non-Hispanic Black men in the South and further research addressing the increased KS [Kaposi sarcoma] incidence and burden in this vulnerable population are needed,” the researchers concluded.

Disclosures: One study author declared affiliations with biotech, pharmaceutical, and/or device companies. Please see the original reference for a full list of disclosures.


Suk R, White DL, Knights S, et al. Incidence trends of Kaposi sarcoma among young non-Hispanic Black men by US regions, 2001-2018. JNCI Cancer Spectr. Published online November 10, 2022. doi:10.1093/jncics/pkac078