(HealthDay News) — A melanoma diagnosis is associated with an increased risk of subsequent prostate cancer, according to a study published in the British Journal of Cancer.

Researchers recruited men from 2006 to 2009 to examine the association between cutaneous melanoma and subsequent risk of prostate cancer.

Data were included from 96,548 eligible patients, of whom 1899 were diagnosed with melanoma during the melanoma diagnosis period. During follow-up, 3677 incident prostate cancers were diagnosed.


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The risk of a subsequent prostate cancer diagnosis was increased for patients with a melanoma diagnosis vs those with no melanoma (fully adjusted hazard ratio, 1.32; 95% CI, 1.09 to 1.60).

The association was also seen if the first melanoma diagnosis was 10 to 15 years before study recruitment (fully adjusted hazard ratio, 2.05; 95% CI, 1.35 to 3.12).

“Our study is the first to show that the positive association between melanoma and the subsequent risk of prostate cancer diagnosis is unlikely to be due to confounding from increased medical surveillance after a melanoma diagnosis,” the authors wrote. “The positive association remained significant even after the over-adjustment for rate of prostate-specific antigen monitoring tests.”

Abstract/Full Text