Risk for head, neck melanoma higher for male sex, older age, non-Hispanic white ethnicity
This study sought to determine gender differences regarding melanoma survivors’ perceptions of partner support and comfort in performing skin self-examinations.
Dose-response association found between indoor tanning and SCC risk among women.
The precision of the targeted methylation sequencing assay for localizing the cancer tissue of origin was reported to be 89%.
The use of steroids for the treatment of immune-related adverse events may have survival consequences.
Antibiotic therapy administered prior to treatment with ICIs was negatively associated with OS across tumor types, as well as tumor response, the researchers noted.
Treatment-free survival could help capture additional perspective about the patient experience during immune checkpoint inhibitor therapy, a study concluded.
Regional variation considerable, with more than threefold variation between regions with highest, lowest use.
A meta-analysis sought to determine if survival is improved with dual targeting of the MAPK pathway with BRAF and MEK inhibitors vs BRAF inhibition alone in patients with advanced melanoma.
The Food and Drug Administration (FDA) has granted accelerated approval to Rozlytrek (entrectinib; Genentech).
The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to bempegaldesleukin (NKTR-214; Nektar Therapeutics and Bristol-Myers Squibb) in combination with nivolumab (Opdivo; Bristol-Myers Squibb) for the treatment of patients with previously untreated unresectable or metastatic melanoma.
Cutaneous SCC risk reduced for highest versus lowest quintile of vitamin A, retinol, some carotenoids.
Researchers sought to determine the risk of disease recurrence in patients with localized melanoma at high risk of disease metastasis.
With the exception of those enrolled in a clinical trial, all patients in this study received systemic monotherapy as first-line treatment of metastatic melanoma.
Calculated tumor area is a novel, microscopic feature and a two-dimensional surrogatefor tumor size.
Approximately one half of all biopsied/excised lesions from patients who have sun-damaged skin are nonmelanocytic.
A comparison of AEDs finds that while most were not associated with skin cancer, carbamazepine and lamotrigine were associated with squamous cell carcinoma.
In the modern era of therapeutic agents, metastasectomy was still associated with improved survival outcomes for patients with stage IV melanoma.
Secondary end points were not significantly different between the 2 groups, including overall survival.
The combination of ipilimumab and nivolumab resulted in a higher rate of objective remissions compared with ipilimumab alone.