Latest Skin Cancer, Basal Cell Carcinoma & Mesothelioma News

Are patients who have received fewer prior medications better candidates for the receipt of CAR-T therapies?

Selumetinib Deemed Effective in Pediatric Inoperable Plexiform Neurofibromas

April 2, 2020

A phase 2 trial demonstrated tumor shrinkage and improvement in reported outcomes in children with inoperable plexiform neurofibromas associated with neurofibromatosis type 1.

Combining PD-1 blockade with PAK4 inhibitors could boost the number of patients helped by the therapy.

Minority of Melanomas With Complete Response to Anti–PD-1 Relapsed After Drug Cessation

March 23, 2020

More research is needed to define criteria for stopping therapy.

Hydrochlorothiazide Exposure May Be Associated With Increased Risk of Nonmelanoma Skin Cancer

March 12, 2020

In this study, oral cancer risk was used as a negative control since it is not associated with increased exposure to UV radiation.

A recent study documents a downward trend in melanoma incidence in adolescents and young adults, but experts disagree about the causes.

What Contributed to the Decrease in Melanoma Incidence in Younger Individuals?

March 6, 2020

A recent study documents a downward trend in melanoma incidence in adolescents and young adults, but experts disagree about the causes.

Drug companies are gathering and including expanded access data in drug submissions as real-world data, but the purpose of expanded access was never for the purpose of research.

A New Trend in Drug Development: Leveraging Data from Expanded Access

March 2, 2020

Drug companies are gathering and including expanded access data in drug submissions as real-world data, but the purpose of expanded access was never for the purpose of research.

New research shows that B cells — and not just T cells — influence whether patients respond to immunotherapy in melanoma, sarcoma, and kidney cancers.

Evidence Suggests B Cells Play a Role in Immunotherapy Response

February 24, 2020

New research shows that B cells — and not just T cells — influence whether patients respond to immunotherapy in melanoma, sarcoma, and kidney cancers.

In the immunotherapy era, the optimal setting and sequencing of BRAF+MEK inhibition remains unresolv

High Cutaneous Melanoma Burden Found Due to UV Radiation

February 19, 2020

Burden varies across states, with highest burden seen in Hawaii.

Treatment-naïve patients with advanced melanoma had significantly better clinical outcomes with nivo

Studies Explore Prevalence of Skin Cancer Among Sexual Minorities

February 13, 2020

Gay, bisexual men have increased odds of skin cancer; OR significantly higher for gender-nonconforming adults.

A new study describes how the flu vaccine creates an antitumoral response in mouse models of metastatic melanoma that has spread to the lungs.

An Early Study Suggests the Flu Shot Could Someday Be Used as Part of an Immunotherapy Regimen in Cancer

February 12, 2020

A new study describes how the flu vaccine creates an antitumoral response in mouse models of metastatic melanoma that has spread to the lungs.

Smartphone Apps Not Accurate Enough to Detect All Melanomas

February 12, 2020

SkinVision had sensitivity of 80 percent, but accuracy poor versus expert recommendation.

Approximately 10% to 20% of all cutaneous melanomas arise in the head and neck region. Melanoma of the neck accounts for 29% of cancers in the head and neck region, and melanoma of the scalp makes up 14% of cancers in that area.

Circulating Tumor Cells Predict Relapse in Stage III Melanoma

February 10, 2020

One or more CTCs independently linked to melanoma relapse at six and 54 months.

Risk Factors Associated With Central Nervous System Metastasis in Stage III Melanoma

February 6, 2020

Researchers aimed to identify clinicopathologic characteristics of patients with stage III melanoma who would benefit from regular CNS imaging.

Higher c-reactive protein (CRP) is associated with worse survival in patients with melanoma.

Blood Mercury Levels Linked to Nonmelanoma Skin Cancer

February 6, 2020

Increased blood total mercury levels, methylmercury levels linked to increased odds of NMSC.

A patient undergoes cancer-related surgery.

Therapeutic Advancements Have Facilitated Surgery Optimization, ASCO Officials Report

February 5, 2020

ASCO outlined advances in oncology that were the most clinically meaningful or had the biggest scientific impact from October 2018 through September 2019.

PAK4 in Melanoma: Could This Target Extend Immunotherapy’s Reach?

February 3, 2020

Combining PD-1 blockade with PAK4 inhibitors could boost the number of patients helped by the therapy.

Ongoing trials, including those that combine immunotherapy with BRAF inhibitors or a triple combinat

Lack of Self-Exams Hampers Early Melanoma Identification

January 21, 2020

Of those surveyed in rural communities, 43 percent intended to perform self-exam but did not follow through.

Improved strategies may be needed for cancer prevention, screening, and surveillance among solid org

Satisfaction High With Mohs Surgery for Melanoma In Situ

January 17, 2020

Short-term, long-term patient satisfaction high with Mohs micrographic surgery for melanoma in situ.

Permanent Chemotherapy-Induced Alopecia: Study Reveals Knowledge and Practice Gaps Occur Across Multiple Disciplines

January 10, 2020

A survey found that dermatologists have more confidence in diagnosing, managing, and their personal knowledge of permanent chemotherapy-induced alopecia compared with clinicians who practice in oncology or primary care/internal medicine.

ASCO officials examined the discrepancies in financial disclosures across platforms and call for a simplified system.

Reporting Mechanisms for Conflict of Interest Disclosures in Medicine Need Standardization

January 8, 2020

ASCO officials examined the discrepancies in financial disclosures across platforms and call for a simplified system.

A nurse confers with a patient about upcoming treatment.

Therapeutic, Survival Outcomes in Advanced Malignant Melanoma Influenced by Facility Volume