This study used data from the Nurses’ Health Study (NHS) and NHS2 to explore the association between height, number of nevi, and risk of invasive melanoma.
Because the TNF-α pathway plays a critical role in tumor surveillance, there is concern that inhibition of this pathway could predispose patients to certain malignancies.
A Penn Medicine team debuts its program focused on cancer care at home — just in time for COVID-19.
Time from diagnosis to definitive surgery is twice as long on average for black versus white patients.
Most studies that have looked at 31-GEP testing in melanoma have been retrospective or prospective, and did not involve a comparator group.
A small phase 1/2 study shows high pCR rates.
The new generation of cancer drugs behave quite differently than cytotoxic therapies, and that may mean phase 1 trials need to be updated.
Previous studies have shown an association between gut microbiome diversity and response to immune checkpoint inhibitor therapy.
Continuous dosing of dabrafenib-trametinib resulted in prolonged PFS compared with intermittent dosing in advanced BRAF-mutated advanced melanoma.
Atezolizumab plus cobimetinib and vemurafenib prolonged PFS in unresectable or metastatic melanoma compared with placebo and BRAF/MEK inhibition in the phase 3 IMspire150 trial.
Although allogeneic HCT is associated with increased risk for keratinocyte carcinoma, the magnitude of risk linked to certain patient characteristics is still unknown.
There was no increase in survival linked to acquired subclinical thyroid dysfunction or preexisting thyroid dysfunction, however.
Imaging radiomics and blood markers could differentiate pseudoprogression.
Many patients with vitiligo undergo multiple courses of phototherapy, which may raise concerns about their risk of photocarcinogenesis.
A phase 2 trial demonstrated tumor shrinkage and improvement in reported outcomes in children with inoperable plexiform neurofibromas associated with neurofibromatosis type 1.
More research is needed to define criteria for stopping therapy.
In this study, oral cancer risk was used as a negative control since it is not associated with increased exposure to UV radiation.
A recent study documents a downward trend in melanoma incidence in adolescents and young adults, but experts disagree about the causes.
Drug companies are gathering and including expanded access data in drug submissions as real-world data, but the purpose of expanded access was never for the purpose of research.
New research shows that B cells — and not just T cells — influence whether patients respond to immunotherapy in melanoma, sarcoma, and kidney cancers.