In this study, authors sought to compare the presentation and outcomes of young patients with RCC and they also determined risk factors associated with mortality in RCC patients <21 years of age.

Children and adolescents with RCC present with more advanced disease than those 21–30 years old. In patients <21, mortality was associated with the non–chromophobe histological subtype, stage 4 disease, government insurance, and not undergoing surgery as first line therapy.

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