Preliminary Diagnosis: Osler-Weber-Rendu Disease
I. What imaging technique is first-line for this diagnosis
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Plain radiography.
II. Describe the advantages and disadvantages of this technique for diagnosis of Osler-Weber-Rendu disease.
Advantages
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Quick and relatively inexpensive imaging modality
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Exposes patients to minimal ionizing radiation
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Disadvantages
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Poorly sensitive and specific in detailing and characterizing any potential hereditary hemorrhagic telangiectatic lesions
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Does not offer exquisite visualization and evaluation of the surrounding soft tissues and osseous structures
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Unable to guide treatment and therapy
III. What are the contraindications for the first-line imaging technique?
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No specific contraindications to plain radiography exist. Some institutions may require consent for pregnant women.
IV. What alternative imaging techniques are available?
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CT of the area of interest
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Catheter angiography
V. Describe the advantages and disadvantages of the alternative techniques for diagnosis Osler-Weber-Rendu disease.
CT of the area of interest
Advantages
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Offers exquisite visualization of the surrounding soft tissues, vascular structures, and osseous structures
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May guide treatment
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Relatively quick imaging modality
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Highly sensitive and specific in detecting, diagnosing, and characterizing potential lesions
Disadvantages
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Exposes patients to ionizing radiation.
Catheter angiography
Advantages
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Gold standard in diagnosing and treating patients with Osler-Weber-Rendu disease
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Highly sensitive and specific in detecting and characterizing telangiectatic lesions
Disadvantages
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Invasive procedure and exposes patients to the risks of an invasive procedure
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May expose patients to large amounts of ionizing radiation
VI. What are the contraindications for the alternative imaging techniques?
CT of the area of interest
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May be contraindicated in pregnant patients
Catheter angiography
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May be contraindicated in pregnant patients and those in a hypocoagulable state
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