Preliminary Diagnosis: Pituitary Tumor
I. What imaging technique is first-line for a pituitary tumor?
MRI with contrast and with dynamic phase imaging is the first line modality.
II. Describe the advantages and disadvantages of this technique for diagnosing a pituitary tumor.
Advantages
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Diagnostic in the appropriate clinical setting.
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Can localize the exact area of anatomic abnormality better than any other modality.
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Can evaluate the extent of tumor local invasion in case of pituitary macroadenoma.
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Does not utilize ionizing radiation.
Disadvantages
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Expensive.
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Time consuming.
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Requires significant patient cooperation to minimize motion artifact.
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Patients with severe claustrophobia may require sedation.
III. What are the contraindications for the first-line imaging technique?
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Patients with poor renal function (i.e., GFR < 30) cannot undergo MR contrasted study.
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Patients with non-MR compatible metals and foreign bodies cannot be scanned.
IV. What alternative imaging techniques are available?
CT with contrast
V. Describe the advantages and disadvantages of the alternative techniques for diagnosing a pituitary tumor.
CT with contrast
Advantages
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Quick and inexpensive.
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Can accurately demonstrate both a small adenoma and large macroadenoma.
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Requires less patient cooperation and is less susceptible to motion artifact.
Disadvantages
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Does not provide same level of anatomic detail as MRI.
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Not as sensitive at detecting microadenomas as MRI.
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Exposes the patient to ionizing radiation.
VI. What are the contraindications for the alternative imaging techniques?
CT with contrast
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Contraindicated for pregnant patients.
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Relative contraindication in patients with contrast allergy.
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Relative contraindication in patients with renal failure.
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