Differential Diagnosis
Hepatitis B virus infection
False-positive serologic test for hepatitis B virus
Suggested Additional Lab Testing
Acute hepatitis B
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Patient is positive for IgM antibody to HBV core antigen.
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Patient is usually positive for hepatitis B surface antigen and hepatitis B virus e antigen. Presence of the e antigen indicates a high degree of infectivity.
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Patient is likely to be positive for serum HBV DNA; level can be followed to assess response to therapy.
Chronic hepatitis B
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Liver function tests, especially aminotransferases, are likely to be elevated for more than 6 months.
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Hepatitis B surface antigen is positive for more than 6 months.
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Chronic cases are also positive for anti-HBV core antigen as total antibody or as IgG.
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