Differential Diagnosis
Gastric ulcer
Duodenal ulcer
Suggested Additional Lab Testing
For gastric ulcer:
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Endoscopy to visualize the ulcer; biopsy of the lesion is recommended to determine if patient has gastric adenocarcinoma.
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Rapid urease test of biopsy material (CLO test) verifies the presence of active infection.
For duodenal ulcer disease:
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Urea breath test is a sensitive and specific test for detection of active infection without the use of biopsy in patients with uncomplicated duodenal ulcer.
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If a biopsy is performed, the CLO test, if positive, verifies the presence of active infection.
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