BAVENCIO (avelumab) for Merkel Cell Carcinoma

This slideshow reviews drug information for BAVENCIO (avelumab), indicated for merkel cell carcinoma. Table of Contents Slide 3: Indication, Dosage, and AdministrationSlide 10: Use in Specific PopulationsSlide 13: Clinical PharmacologySlide 17: Warnings and PrecautionsSlide 22: Clinical Safety and EfficacySlide 30: Drug Storage and SupplySlide 33: References

IMLYGIC (talimogene laherparepvec) for Melanoma

This slideshow reviews drug information for IMLYGIC (talimogene laherparepvec), indicated for melanoma. Table of Contents Slide 3: Indication, Dosage, and AdministrationSlide 10: Use in Specific PopulationsSlide 13: Clinical PharmacologySlide 17: Warnings and PrecautionsSlide 21: Clinical Safety and EfficacySlide 27: Drug Storage and SupplySlide 30: References

ONIVYDE (liposomal irinotecan) for Pancreatic Cancer

This slideshow reviews drug information for ONIVYDE (liposomal irinotecan), indicated for pancreatic cancer. Table of Contents Slide 3: Indication, Dosage, and AdministrationSlide 8: Use in Specific PopulationsSlide 11: Clinical PharmacologySlide 16: Warnings and PrecautionsSlide 20: Clinical Safety and EfficacySlide 27: Drug Storage and SupplySlide 30: References

ERIVEDGE (vismodegib) for Basal Cell Carcinoma

This slideshow reviews drug information for ERIVEDGE (vismodegib), indicated for basal cell carcinoma. Table of Contents Slide 3: Indication, Dosage, and AdministrationSlide 7: Use in Specific PopulationsSlide 10: Clinical PharmacologySlide 14: Warnings and PrecautionsSlide 19: Clinical Safety and EfficacySlide 25: Drug Storage and SupplySlide 28: References

CAPRELSA (vandetanib) for Medullary Thyroid Cancer

This slideshow reviews drug information for CAPRELSA (vandetanib), indicated for medullary thyroid cancer. Table of Contents Slide 3: Indication, Dosage, and AdministrationSlide 9: Use in Specific PopulationsSlide 12: Clinical PharmacologySlide 17: Warnings and PrecautionsSlide 23: Clinical Safety and EfficacySlide 29: Drug Storage and SupplySlide 32: References


57% of respondents indicated that they discuss obesity with their patients after they are diagnosed with cancer, however nearly 40% of those polled indicated that they do not discuss the topic.

Discussing Obesity With Patients With Cancer

The American Society of Clinical Oncology recently released a position statement on obesity and cancer. While research related to obesity’s effect on cancer is ongoing, it is clear that obesity is becoming a leading preventable cause of cancer (overtaking more well-known causes such as tobacco) and it’s an important issue for oncologists to be informed…
The consensus from our audience was almost exactly evenly split between discussing palliative care with patients at the beginning of treatment and after all treatment options have failed.Recent research, however, suggests that palliative care as a method to ease the symptoms of cancer treatment is most effective at the onset of treatment.

Physician Communication and Patient Comprehension of Palliative Care

The Palliative Care in Oncology Symposium recently took place in Boston, Massachusetts, and focused on patient-centered care across the cancer continuum. With this in mind, Cancer Therapy Advisor conducted a community poll that asked our readers about their experience in dealing with issues surrounding the discussion of palliative care with their patients.


National Library of Medicine makes Medical Literature Analysis and Retrieval System (MEDLARS) operational. Image courtesy of the National Library of Medicine.

Notable Electronic Health Record Milestones

Since 2008, electronic health record adoption has increased 41% — an rise attributable to a mandate from the U.S. government and paid incentives to doctors’ offices and health care provider networks to make investments in the technology. Although there’s still a long road ahead in terms of achieving meaningful use incentives, this slideshow explores the…
RT can be used to eliminate lingering cancer cells, prevent cancer metastasis, and shrink tumors for symptom relief or tumor resection.2

Radiation Therapy

Radiation therapy (RT) utilizes high energy beams or charged particles to damage DNA and generate free radicals from cell water that can harm cancer cells.1 Cancer cells are more vulnerable to radiation due to the faster rate of cancer cell division.1 This slideshow reviews the uses, benefits, types, side effects, and toxicities associated with radiation…
Caretakers were found to have poor nutrition as well, because their food intake changed to accommodate their patient’s appetite. They also felt powerless, incompetent, and rejected when their patients refused to eat, which often led to relationship conflict.3

Cancer Cachexia

Cancer cachexia is a complex metabolic reaction characterized as a decrease in lipogenesis and muscle proteins, as well as an increase in acute phase proteins, energy expenditure, proteolysis, glucose turnover, lipolysis, and ketone bodies caused by a combination of the malignancy and the treatment of the cancer itself.4 As a result, patients present with anorexia…
In patients with cancer, complementary and alternative medicine (CAM) generally focuses on improving cancer-associated symptoms such as anxiety, pain, fatigue, nausea, stress, as well as sleep and mood disturbances.1

Complementary and Alternative Medicine in Cancer

Complementary and alternative medicine (CAM) is used as an adjunct to traditional therapies in an effort to provide supportive care in improving symptom control and patient well-being.1 Incorporating CAM in oncology has led to the development of integrative oncology where an emphasis is also placed in the emotional, spiritual, and mental needs of patients with…
Slide 1: Fatigue

14 Chemotherapy-Related Adverse Effects

Patients receiving treatment for cancer can experience a number of potential side effects and reactions. Clinicians should be aware of the adverse events that can result from administration of certain agents. Fatigue can result from a number of factors, including anemia, depression, and radiation therapy.1 Similarly, alopecia affects many patients and can be one of…
Hair has been a social symbol throughout time, cultivating perceptions of age, social status, beliefs, and more importantly, individuality and a sense of attractiveness.1

Chemotherapy Induced Alopecia (CIA)

Compared to the severe adverse effects of chemotherapy, chemotherapy-induced alopecia (CIA) is surprisingly one of the more troubling aspects of chemotherapy to patients.[2] (Slide 1) In a study of 18- to 38-year-old males and females with cancer, both genders expressed feelings of being exposed and judged.[9] Normal hair growth is comprised of three phases: 1)…

Managing Neutropenia in a Patient with Abdominal Pain Following Chemotherapy

Chief Complaint MP is a 38-year-old woman who comes to the clinic with a temperature of 101F and complains of abdominal pain approximately 14 days after her last chemotherapy treatment. Results of Last Visit During her last appointment, MP denied fevers, chills, or other signs/symptoms of infection but, due to laboratory results, was initiated on…
The chemotherapy drugs fluorouracil (Carac, Effudex, Fluoroplex, generics), vinorelbine (Navelbine, generics), and daunorubicin (Cerubidine, Daunoxome) cause hyperpigmentation of the skin, nails, and oral mucosa. Hyperpigmentation can follow the distribution of veins, known as serpentine supravenous hyperpigmentation, or can be patchy and macular. Topical hydroquinone can decrease melanin production and help clear hyperpigmentation. The disorder typically resolves when chemotherapy is stopped.

Chemotherapy-Related Skin Toxicities

The incidence of cancer diagnoses is increasing worldwide as the world’s population grows and people continue to live longer. As a result, chemotherapy-related skin toxicities are on the rise and clinicians and patients alike should be prepared to recognize these disorders.
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