Study Finds Patients With Rare Ovarian Cancer Develop Chemoresistance
Patients with low-grade serous carcinoma of the ovary or peritoneum (LGSC) developed chemoresistance to neoadjuvant platinum-based therapy.
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Plasma DNA Assay Accurately Identifies Renal Cell Carcinoma
An assay that measures tumor-derived cell-free DNA in plasma discriminated between patients with and without renal cell carcinoma with 99% accuracy.
How Cancer Care Can Affect the Kidney
Recent advances in cancer management may present challenges for nephrologists.
Venetoclax With Chemotherapy: Promising for Elderly Patients With AML?
Combined with chemotherapy, venetoclax appears to be effective for treating AML among fit elderly patients.
Restructured Process Overcomes Barriers to Prior Authorization for Proton Therapy
This study examined the impact of a restructured prior authorization process on the delivery of PBT at a proton therapy center.
Adding Radiotherapy to Chemotherapy Boosts Survival in Nasopharyngeal Carcinoma
Patients treated with chemotherapy plus radiotherapy had a 64% reduced likelihood of disease progression or death compared with those who underwent chemotherapy alone.
A 6-Gene Expression Signature May Predict Benefit From Induction Chemotherapy in Locally Advanced Nasopharyngeal Cancer
The purpose of this study was to develop and test a gene-expression profiling assay to facilitate patient selection for induction chemotherapy in the setting of LA-NPC.
Improving Diagnosis and Staging Times for Patients With Suspected Lung Cancer
Standardized triage process significantly improved timeliness of diagnosis and staging of suspected lung cancer at a rapid assessment clinic.
Shorter PSA Doubling Time Predicts Worse Outcomes in nmCRPC
In men with nonmetastatic castration-resistant prostate cancer, a PSA doubling time of less than 3 months vs 15 months or more increases the risk of metastasis, which in turn is associated with a large increase in healthcare utilization and costs.
MRI Useful for Diagnosing Muscle-Invasive Bladder Cancer
Multiparametric magnetic resonance imaging is highly accurate in differentiating nonmuscle-invasive from muscle-invasive bladder cancer, according to a new systematic review and meta-analysis.
COVID-19 Case Fatality Rate 29 Percent in Multiple Myeloma Patients
Increased odds of adverse outcomes seen for Hispanic/Latinos, African-American Blacks versus white patients.
Hyperthyroidism Therapies Not Linked to Solid Cancer Mortality
A team of investigators conducted a multicenter cohort study to determine if a relationship existed between treatment for hyperthyroidism and risk of death from solid cancer.
New Evidence Supports Update of ASCO Guidelines on Prevention, Treatment of CIPN
A literature search of new studies clarifies, refutes, and expands on previous recommendations for managing new and established CIPN in patients treated with cytotoxic agents.
Glasgow Prognostic Score Predicts Adverse Pathology, Survival in UTUC
In a study, modified Glasgow prognostic score predicted nonorgan-confined disease and lymph node invasion at surgery.
Two Trials Evaluate CAR-T Cell Therapy for Relapsed/Refractory Hodgkin Lymphoma
CD30 CAR-T cell treatment after lymphodepletion may produce antitumor activity without significant toxicity in relapsed or refractory Hodgkin lymphoma.
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