Latest News

Biomarker-Guided ICI Therapy Provides Greater Benefit in Cancer Patients

By

Andrea S. Blevins Primeau, PhD, MBA

Cancer patients with biomarker-positive tumors have better outcomes on immune checkpoint inhibitor therapy, a meta-analysis suggests.

CIRS-G Reveals Accelerated Aging, Early Death in Childhood Cancer Survivors

By

Andrea S. Blevins Primeau, PhD, MBA

Researchers have used a geriatric rating scale to show that childhood cancer survivors experience accelerated aging and have a higher risk of premature death than the general population.

Palliative Care Does Not Improve HRQOL in Context of Gastrointestinal Cancer Surgery

By

Leah Lawrence

Palliative care does not improve health-related quality of life among patients undergoing curative-intent surgery for upper gastrointestinal cancer, a study suggests.

Taking Vitamin D₃ Supplements Daily May Reduce Risk of Cancer Death

There was a 12% reduction in the risk of cancer death among patients who took vitamin D₃ supplements daily.

Repotrectinib Gets Priority Review for ROS1-Positive NSCLC

By

Brian Park, PharmD

A regulatory decision is expected on November 27, 2023.

US COVID-19 Hospitalizations Drop Below 9000, Potentially Due to Change in Testing

Hospitalizations are among the few COVID-19 metrics still being monitored by public health officials.

Switching ET and Adding Ribociclib Improves PFS in HR+, HER2- Breast Cancer

By

Andrea S. Blevins Primeau, PhD, MBA

Patients with HR+, HER2- metastatic breast cancer whose disease progressed on endocrine therapy (ET) and a CDK4/6 inhibitor have better progression-free survival if they switch ET and receive ribociclib than if they switch ET alone, a phase 2 study suggests.

Targeted Adjuvant Therapies Provide No Survival Benefit in Stage III Melanoma

By

Leah Lawrence

Targeted adjuvant therapy does not improve outcomes in patients with stage III melanoma, results of a Swedish study suggest.

Lung Cancer Survival by Smoking Status and Other Risk Factors

By

Leah Lawrence

A new study quantified survival in lung cancer patients by smoking status and revealed other potentially actionable risk factors associated with survival.

Imaging Agent Posluma Approved to Aid in Prostate Cancer Detection

By

Diana Ernst, RPh

The approval was based on data from the LIGHTHOUSE and SPOTLIGHT trials.

Phone Intervention Decreases ED Visits, Hospitalizations in Head and Neck Cancer

By

Jessica Nye, PhD

A phone intervention can decrease ED visits and hospital admissions in head and neck cancer patients receiving radiation therapy, a study suggests.

Second-Generation Antiandrogens Linked to Falls, Cognitive Toxicity in Prostate Cancer Patients

By

Leah Lawrence

Prostate cancer patients treated with second-generation antiandrogens may have an increased risk of falls, fatigue, and cognitive toxicity.

Olvimulogene Nanivacirepvec May Reverse Platinum Resistance, Refractoriness in Ovarian Cancer

By

Andrea S. Blevins Primeau, PhD, MBA

Olvimulogene nanivacirepvec plus platinum-based chemotherapy and bevacizumab appears effective in platinum-resistant or -refractory ovarian cancer.

Genomic Profiling in Cancer of Unknown Primary Feasible but Challenging

By

Leah Lawrence

Genomic profiling can reveal actionable mutations in patients with cancer of unknown primary but can be limited by a lack of sufficient tissue, research suggests.

Anti-PD-L1 Combinations Produce Mixed Results in Metastatic RCC

By

Leah Lawrence

Anti-PD-L1-based therapies may improve some outcomes over sunitinib in patients with metastatic renal cell carcinoma, a meta-analysis suggests.

Microdosed Incisional Clindamycin Cuts SSI After Skin Cancer Surgery

For patients undergoing skin cancer surgery, microdosed incisional clindamycin reduced the rate of surgical site infections.

COVID-19 Pandemic Created Challenges for Interpreting Trends in Cancer Incidence

By

Andrea S. Blevins Primeau, PhD, MBA

The COVID-19 pandemic caused reductions in cancer diagnoses in 2020 that may pose challenges for interpreting long-term cancer trends.

Medicaid Expansion Tied to Decrease in Distant Stage Cancer Diagnoses and Deaths

By

Leah Lawrence

Medicaid expansion was associated with a decrease in the incidence of distant stage cancer and cancer death, according to new research.

Neuroblastoma Survivors Report Neurocognitive Impairment, Failure to Reach Milestones

By

Leah Lawrence

Survivors of childhood neuroblastoma have neurocognitive impairments that affect their ability to reach adult milestones, a study suggests.

Real-World mCSPC First-Line Treatment Intensification Remains Low

By

Natasha Persaud

Study findings highlight the need for earlier mCSPC treatment intensification by urologists and oncologists.