The 2-year overall survival rate was 32.5%.
Researchers found that, in 18% of recurrences, the new tumor was molecularly unrelated to the original tumor.
Researchers sought to determine gene regulation patterns that may help predict response to CAR-T therapy in patients with acute lymphoblastic leukemia.
Researchers sought to determine if there are racial disparities in treatment with bone-modifying agents for patients with multiple myeloma.
CoVac-1, a peptide-based COVID-19 vaccine, induced T-cell responses in patients with B-cell deficiencies.
Researchers sought to determine risk factors for relapse in patients with ALL.
Three biomarkers were associated with prognosis after COVID-19 treatment.
Researchers sought to determine the predictors of mortality during hospital stays in patients with multiple myeloma.
Ipilimumab plus nivolumab demonstrated efficacy in a phase 2 trial of patients with advanced melanoma who failed prior anti-PD-1 therapy.
Adding toripalimab to standard chemotherapy extended progression-free survival by 13.2 months.
Adding adebrelimab to chemotherapy nearly doubled the 2-year overall survival rate and more than tripled the 1-year progression-free survival rate.
Canakinumab did not improve response rates, progression-free survival, or overall survival.
Adding nivolumab to chemotherapy improved the pathologic complete response rate and prolonged event-free survival.
Pediatric cancer patients in low- and middle-income countries had a nearly 16-fold higher risk of all-cause mortality within 30 days of presentation, when compared with their counterparts in high-income countries.
In the year before the RACE Act was implemented, none of the approved therapies required pediatric study, but 92% of them had a mechanism of action that would necessitate pediatric studies under the RACE Act.
Patients who received treatment selected by the ChemoID assay had superior progression-free survival and overall survival.
AI models could enable earlier detection of pancreatic cancer and improve treatment options for patients, according to researchers.