American Society for Radiation Oncology (ASTRO) 2022 Coverage

SBRT for Oligoprogression Improves Outcomes in NSCLC but Not Breast Cancer

Treating oligoprogression with SBRT improved progression-free survival in patients with lung cancer but not in those with breast cancer.

Long-Term Data Support HFRT as Standard Care in High-Risk Prostate Cancer

Hypofractionated radiotherapy produces similar long-term outcomes as conventionally fractionated radiotherapy in high-risk prostate cancer, a phase 3 study suggests.

Radiotherapy of Asymptomatic Bone Metastases Reduces Skeletal-Related Events

Prophylactic radiotherapy of asymptomatic bone metastases can reduce skeletal-related events and improve survival in patients with solid tumors, a study suggests.

Radiation to Celiac Plexus Reduces Pancreatic Cancer-Associated Pain

Delivery of radiation to the celiac plexus can decrease pain and opioid use among patients with pancreatic cancer, a phase 2 study suggests.

Durvalumab Plus IMRT No Better Than Cetuximab Plus IMRT in Head and Neck Cancer

Durvalumab plus IMRT proved no more effective than cetuximab plus IMRT in patients with treatment-naïve, locoregionally advanced head and neck squamous cell carcinoma.

SBRT Proposed as Standard Treatment Option for Advanced Hepatocellular Carcinoma

Adding stereotactic body radiation therapy to sorafenib improves survival outcomes in patients with advanced hepatocellular carcinoma, a phase 3 trial suggests.

Concurrent Radiation Boost Comparable to Sequential Boost in High-Risk Breast Cancer

A concurrent radiation boost produces comparable outcomes as a sequential boost in patients with high-risk breast cancer, a phase 3 study suggests.

S-1-Based Chemoradiotherapy Improves Outcomes in Elderly Patients With Esophageal Squamous Cell Carcinoma

Adding oral S-1 chemotherapy to radiotherapy can improve outcomes in elderly patients with inoperable esophageal squamous cell carcinoma.

Proton FLASH Radiotherapy Deemed Feasible, Comparable to Conventional Dose Rate Radiotherapy

Proton FLASH radiotherapy is feasible, safe, and provides pain relief for cancer patients with bone metastases, according to a first-in-human trial.

Ultra-Low-Dose Radiation Appears Effective in Orbital Indolent B-Cell Lymphoma

Response-adapted ultra-low-dose radiation therapy demonstrated efficacy and negligible toxicity in orbital indolent B-cell lymphoma.